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mtnN protein (Desulfovibrio salexigens) - STRING interaction network
"mtnN" - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase in Desulfovibrio salexigens
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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mtnN5’-methylthioadenosine/S-adenosylhomocysteine nucleosidase; Catalyzes the irreversible cleavage of the glycosidic bond in both 5’-methylthioadenosine (MTA) and S- adenosylhomocysteine (SAH/AdoHcy) to adenine and the corresponding thioribose, 5’-methylthioribose and S-ribosylhomocysteine, respectively; Belongs to the PNP/UDP phosphorylase family. MtnN subfamily (231 aa)    
Predicted Functional Partners:
luxS
S-ribosylhomocysteine lyase; Involved in the synthesis of autoinducer 2 (AI-2) which is secreted by bacteria and is used to communicate both the cell density and the metabolic potential of the environment. The regulation of gene expression in response to changes in cell density is called quorum sensing. Catalyzes the transformation of S-ribosylhomocysteine (RHC) to homocysteine (HC) and 4,5- dihydroxy-2,3-pentadione (DPD); Belongs to the LuxS family (159 aa)
 
   
  0.993
ahcY
Adenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine (472 aa)
       
  0.910
Desal_1601
Purine nucleoside phosphorylase; Purine nucleoside phosphorylase involved in purine salvage (248 aa)
       
  0.907
mtaD
5-methylthioadenosine/S-adenosylhomocysteine deaminase; Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine; Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family (442 aa)
       
  0.906
Desal_3757
PFAM- Acyl transferase; KEGG- dvl-Dvul_1813 malonyl CoA-acyl carrier protein transacylase (307 aa)
   
        0.744
Desal_3810
Pyridoxal phosphate homeostasis protein; Pyridoxal 5’-phosphate (PLP)-binding protein, which is involved in PLP homeostasis (234 aa)
 
        0.743
Desal_3661
PFAM- homocysteine S-methyltransferase; cobalamin B12-binding domain protein; Methionine synthase B12-binding module cap domain protein; dihydropteroate synthase DHPS; KEGG- dde-Dde_2115 methionine synthase (B12-dependent) (806 aa)
         
  0.731
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (904 aa)
   
   
  0.683
Desal_3752
Transcriptional regulator, LysR family; PFAM- LysR substrate-binding; regulatory protein LysR; KEGG- dal-Dalk_2139 transcriptional regulator, LysR family (315 aa)
         
  0.586
nadE
Glutamine-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source (549 aa)
   
 
  0.475
Your Current Organism:
Desulfovibrio salexigens
NCBI taxonomy Id: 526222
Other names: D. salexigens DSM 2638, Desulfovibrio salexigens, Desulfovibrio salexigens ATCC 14822, Desulfovibrio salexigens DSM 2638, Desulfovibrio salexigens DSM2638, Desulfovibrio salexigens str. DSM 2638, Desulfovibrio salexigens strain DSM 2638
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