node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Bmur_0717 | Bmur_2357 | Bmur_0717 | Bmur_2357 | TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain IV; protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; KEGG: bhy:BHWA1_02429 translation elongation factor G; SMART: elongation factor G domain IV; elongation factor G domain protein. | KEGG: bhy:BHWA1_01174 endoribonuclease; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | 0.869 |
Bmur_0717 | guaA | Bmur_0717 | Bmur_2315 | TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain IV; protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; KEGG: bhy:BHWA1_02429 translation elongation factor G; SMART: elongation factor G domain IV; elongation factor G domain protein. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.680 |
Bmur_0717 | metG | Bmur_0717 | Bmur_1255 | TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain IV; protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; KEGG: bhy:BHWA1_02429 translation elongation factor G; SMART: elongation factor G domain IV; elongation factor G domain protein. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.505 |
Bmur_1523 | Bmur_2357 | Bmur_1523 | Bmur_2357 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | KEGG: bhy:BHWA1_01174 endoribonuclease; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | 0.537 |
Bmur_1523 | apt | Bmur_1523 | Bmur_1596 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.517 |
Bmur_1523 | guaA | Bmur_1523 | Bmur_2315 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.658 |
Bmur_2357 | Bmur_0717 | Bmur_2357 | Bmur_0717 | KEGG: bhy:BHWA1_01174 endoribonuclease; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | TIGRFAM: small GTP-binding protein; PFAM: elongation factor G domain IV; protein synthesis factor GTP-binding; elongation factor G domain protein; elongation factor Tu domain 2 protein; KEGG: bhy:BHWA1_02429 translation elongation factor G; SMART: elongation factor G domain IV; elongation factor G domain protein. | 0.869 |
Bmur_2357 | Bmur_1523 | Bmur_2357 | Bmur_1523 | KEGG: bhy:BHWA1_01174 endoribonuclease; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.537 |
Bmur_2357 | Bmur_2653 | Bmur_2357 | Bmur_2653 | KEGG: bhy:BHWA1_01174 endoribonuclease; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | KEGG: bhy:BHWA1_00066 diaminopropionate ammonia- lyase; TIGRFAM: diaminopropionate ammonia-lyase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.413 |
Bmur_2357 | apt | Bmur_2357 | Bmur_1596 | KEGG: bhy:BHWA1_01174 endoribonuclease; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | 0.803 |
Bmur_2357 | aroD | Bmur_2357 | Bmur_2355 | KEGG: bhy:BHWA1_01174 endoribonuclease; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | 3-dehydroquinate dehydratase, type I; Involved in the third step of the chorismate pathway, which leads to the biosynthesis of aromatic amino acids. Catalyzes the cis- dehydration of 3-dehydroquinate (DHQ) and introduces the first double bond of the aromatic ring to yield 3-dehydroshikimate. Belongs to the type-I 3-dehydroquinase family. | 0.437 |
Bmur_2357 | aroE | Bmur_2357 | Bmur_2356 | KEGG: bhy:BHWA1_01174 endoribonuclease; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.572 |
Bmur_2357 | fusA | Bmur_2357 | Bmur_1833 | KEGG: bhy:BHWA1_01174 endoribonuclease; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | Translation elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 s [...] | 0.869 |
Bmur_2357 | guaA | Bmur_2357 | Bmur_2315 | KEGG: bhy:BHWA1_01174 endoribonuclease; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.428 |
Bmur_2357 | metG | Bmur_2357 | Bmur_1255 | KEGG: bhy:BHWA1_01174 endoribonuclease; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.427 |
Bmur_2357 | nnrD | Bmur_2357 | Bmur_2660 | KEGG: bhy:BHWA1_01174 endoribonuclease; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | Carbohydrate kinase, YjeF related protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. In the C-terminal section; belongs to the NnrD/CARKD family. | 0.515 |
Bmur_2653 | Bmur_2357 | Bmur_2653 | Bmur_2357 | KEGG: bhy:BHWA1_00066 diaminopropionate ammonia- lyase; TIGRFAM: diaminopropionate ammonia-lyase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | KEGG: bhy:BHWA1_01174 endoribonuclease; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | 0.413 |
apt | Bmur_1523 | Bmur_1596 | Bmur_1523 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.517 |
apt | Bmur_2357 | Bmur_1596 | Bmur_2357 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | KEGG: bhy:BHWA1_01174 endoribonuclease; TIGRFAM: endoribonuclease L-PSP; PFAM: Endoribonuclease L-PSP. | 0.803 |
apt | guaA | Bmur_1596 | Bmur_2315 | Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis. | GMP synthase, large subunit; Catalyzes the synthesis of GMP from XMP. | 0.998 |