node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gobs_2707 | Gobs_2708 | Gobs_2707 | Gobs_2708 | PFAM: thymidine kinase; KEGG: stp:Strop_2343 thymidine kinase. | PFAM: major facilitator superfamily MFS_1; KEGG: sco:SCO1420 integral membrane protein. | 0.648 |
Gobs_2707 | Gobs_3391 | Gobs_2707 | Gobs_3391 | PFAM: thymidine kinase; KEGG: stp:Strop_2343 thymidine kinase. | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: kra:Krad_4541 5'-nucleotidase domain- containing protein; Belongs to the 5'-nucleotidase family. | 0.907 |
Gobs_2707 | Gobs_4378 | Gobs_2707 | Gobs_4378 | PFAM: thymidine kinase; KEGG: stp:Strop_2343 thymidine kinase. | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.910 |
Gobs_2707 | Gobs_4398 | Gobs_2707 | Gobs_4398 | PFAM: thymidine kinase; KEGG: stp:Strop_2343 thymidine kinase. | KEGG: nca:Noca_3535 thymidine phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like. | 0.944 |
Gobs_2707 | Gobs_4399 | Gobs_2707 | Gobs_4399 | PFAM: thymidine kinase; KEGG: stp:Strop_2343 thymidine kinase. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.928 |
Gobs_2707 | dut | Gobs_2707 | Gobs_1871 | PFAM: thymidine kinase; KEGG: stp:Strop_2343 thymidine kinase. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.978 |
Gobs_2707 | prfA | Gobs_2707 | Gobs_4148 | PFAM: thymidine kinase; KEGG: stp:Strop_2343 thymidine kinase. | Peptide chain release factor 1; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. | 0.846 |
Gobs_2707 | thyA | Gobs_2707 | Gobs_3946 | PFAM: thymidine kinase; KEGG: stp:Strop_2343 thymidine kinase. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.974 |
Gobs_2707 | tmk | Gobs_2707 | Gobs_0609 | PFAM: thymidine kinase; KEGG: stp:Strop_2343 thymidine kinase. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.922 |
Gobs_2707 | tmk-2 | Gobs_2707 | Gobs_4597 | PFAM: thymidine kinase; KEGG: stp:Strop_2343 thymidine kinase. | Major facilitator superfamily MFS_1; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.922 |
Gobs_2708 | Gobs_2707 | Gobs_2708 | Gobs_2707 | PFAM: major facilitator superfamily MFS_1; KEGG: sco:SCO1420 integral membrane protein. | PFAM: thymidine kinase; KEGG: stp:Strop_2343 thymidine kinase. | 0.648 |
Gobs_3391 | Gobs_2707 | Gobs_3391 | Gobs_2707 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: kra:Krad_4541 5'-nucleotidase domain- containing protein; Belongs to the 5'-nucleotidase family. | PFAM: thymidine kinase; KEGG: stp:Strop_2343 thymidine kinase. | 0.907 |
Gobs_3391 | Gobs_4378 | Gobs_3391 | Gobs_4378 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: kra:Krad_4541 5'-nucleotidase domain- containing protein; Belongs to the 5'-nucleotidase family. | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.923 |
Gobs_3391 | Gobs_4398 | Gobs_3391 | Gobs_4398 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: kra:Krad_4541 5'-nucleotidase domain- containing protein; Belongs to the 5'-nucleotidase family. | KEGG: nca:Noca_3535 thymidine phosphorylase; TIGRFAM: pyrimidine-nucleoside phosphorylase; PFAM: glycosyl transferase family 3; Pyrimidine nucleoside phosphorylase domain; Glycosyl transferase, family 3-like. | 0.914 |
Gobs_3391 | Gobs_4399 | Gobs_3391 | Gobs_4399 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: kra:Krad_4541 5'-nucleotidase domain- containing protein; Belongs to the 5'-nucleotidase family. | Cytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. | 0.912 |
Gobs_3391 | dut | Gobs_3391 | Gobs_1871 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: kra:Krad_4541 5'-nucleotidase domain- containing protein; Belongs to the 5'-nucleotidase family. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.900 |
Gobs_3391 | thyA | Gobs_3391 | Gobs_3946 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: kra:Krad_4541 5'-nucleotidase domain- containing protein; Belongs to the 5'-nucleotidase family. | Thymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.909 |
Gobs_3391 | tmk | Gobs_3391 | Gobs_0609 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: kra:Krad_4541 5'-nucleotidase domain- containing protein; Belongs to the 5'-nucleotidase family. | Thymidylate kinase; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.912 |
Gobs_3391 | tmk-2 | Gobs_3391 | Gobs_4597 | PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: kra:Krad_4541 5'-nucleotidase domain- containing protein; Belongs to the 5'-nucleotidase family. | Major facilitator superfamily MFS_1; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.912 |
Gobs_4378 | Gobs_2707 | Gobs_4378 | Gobs_2707 | Purine nucleotide phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | PFAM: thymidine kinase; KEGG: stp:Strop_2343 thymidine kinase. | 0.910 |