node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Gbro_1339 | Gbro_2501 | Gbro_1339 | Gbro_2501 | TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: ppd:Ppro_3458 UvrD/REP helicase. | PFAM: ABC transporter related; KEGG: scl:sce6315 excinuclease ABC subunit A. | 0.635 |
Gbro_1339 | uvrA | Gbro_1339 | Gbro_2851 | TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: ppd:Ppro_3458 UvrD/REP helicase. | Excinuclease ABC, A subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate. | 0.738 |
Gbro_1339 | uvrB | Gbro_1339 | Gbro_2865 | TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: ppd:Ppro_3458 UvrD/REP helicase. | Excinuclease ABC, B subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...] | 0.907 |
Gbro_1339 | uvrC | Gbro_1339 | Gbro_2359 | TIGRFAM: ATP-dependent DNA helicase PcrA; PFAM: UvrD/REP helicase; KEGG: ppd:Ppro_3458 UvrD/REP helicase. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.810 |
Gbro_2354 | Gbro_2357 | Gbro_2354 | Gbro_2357 | KEGG: hdu:HD1162 riboflavin synthase subunit alpha; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein. | PFAM: Protein of unknown function DUF2581. | 0.855 |
Gbro_2354 | Gbro_2360 | Gbro_2354 | Gbro_2360 | KEGG: hdu:HD1162 riboflavin synthase subunit alpha; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein. | Conserved hypothetical protein; Displays ATPase and GTPase activities. | 0.847 |
Gbro_2354 | Gbro_2361 | Gbro_2354 | Gbro_2361 | KEGG: hdu:HD1162 riboflavin synthase subunit alpha; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein. | Protein of unknown function UPF0052 and CofD; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.847 |
Gbro_2354 | ribBA | Gbro_2354 | Gbro_2355 | KEGG: hdu:HD1162 riboflavin synthase subunit alpha; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.999 |
Gbro_2354 | ribH | Gbro_2354 | Gbro_2356 | KEGG: hdu:HD1162 riboflavin synthase subunit alpha; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.999 |
Gbro_2354 | uvrC | Gbro_2354 | Gbro_2359 | KEGG: hdu:HD1162 riboflavin synthase subunit alpha; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.854 |
Gbro_2357 | Gbro_2354 | Gbro_2357 | Gbro_2354 | PFAM: Protein of unknown function DUF2581. | KEGG: hdu:HD1162 riboflavin synthase subunit alpha; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein. | 0.855 |
Gbro_2357 | Gbro_2360 | Gbro_2357 | Gbro_2360 | PFAM: Protein of unknown function DUF2581. | Conserved hypothetical protein; Displays ATPase and GTPase activities. | 0.853 |
Gbro_2357 | Gbro_2361 | Gbro_2357 | Gbro_2361 | PFAM: Protein of unknown function DUF2581. | Protein of unknown function UPF0052 and CofD; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.847 |
Gbro_2357 | ribBA | Gbro_2357 | Gbro_2355 | PFAM: Protein of unknown function DUF2581. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.871 |
Gbro_2357 | ribH | Gbro_2357 | Gbro_2356 | PFAM: Protein of unknown function DUF2581. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.907 |
Gbro_2357 | uvrC | Gbro_2357 | Gbro_2359 | PFAM: Protein of unknown function DUF2581. | Excinuclease ABC, C subunit; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.847 |
Gbro_2360 | Gbro_2354 | Gbro_2360 | Gbro_2354 | Conserved hypothetical protein; Displays ATPase and GTPase activities. | KEGG: hdu:HD1162 riboflavin synthase subunit alpha; TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein. | 0.847 |
Gbro_2360 | Gbro_2357 | Gbro_2360 | Gbro_2357 | Conserved hypothetical protein; Displays ATPase and GTPase activities. | PFAM: Protein of unknown function DUF2581. | 0.853 |
Gbro_2360 | Gbro_2361 | Gbro_2360 | Gbro_2361 | Conserved hypothetical protein; Displays ATPase and GTPase activities. | Protein of unknown function UPF0052 and CofD; Required for morphogenesis under gluconeogenic growth conditions; Belongs to the gluconeogenesis factor family. | 0.949 |
Gbro_2360 | ribBA | Gbro_2360 | Gbro_2355 | Conserved hypothetical protein; Displays ATPase and GTPase activities. | GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.849 |