STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pflA_2Pyruvate formate-lyase 1-activating enzyme; Activation of anaerobic ribonucleoside-triphosphate reductase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine. (168 aa)    
Predicted Functional Partners:
nrdD
Anaerobic ribonucleoside-triphosphate reductase.
 
  
 0.968
cobU
Bifunctional adenosylcobalamin biosynthesis protein CobU.
   
    0.789
nifJ
Pyruvate-flavodoxin oxidoreductase.
     
 0.593
ACWI_27780
5'-nucleotidase.
 
      0.534
adhE_3
Aldehyde-alcohol dehydrogenase.
 
  
 0.530
nasB
Assimilatory nitrate reductase electron transfer subunit.
  
  
 0.512
sucD
Succinate-semialdehyde dehydrogenase (acetylating).
 
  
 0.492
hcaC
3-phenylpropionate/cinnamic acid dioxygenase ferredoxin subunit.
   
  
 0.490
hcnB_2
Hydrogen cyanide synthase subunit HcnB.
  
  
 0.480
cobB_1
Cobyrinic acid A,C-diamide synthase; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
   
  
 0.476
Your Current Organism:
Acetobacterium wieringae
NCBI taxonomy Id: 52694
Other names: A. wieringae, ATCC 43740, JCM 2380, LMG 7579, LMG:7579, strain C
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