STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SIRT5NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Has weak NAD-dependent protein deacetylase activity; however this activity may not be physiologically relevant in vivo. (306 aa)    
Predicted Functional Partners:
ENSSMAP00000005572
Sirtuin 6.
  
0.939
ENSSMAP00000000308
Sirtuin 2 (silent mating type information regulation 2, homolog) 2 (S. cerevisiae).
  
 
0.934
SMAX5B_001662
Putative NAD-dependent protein deacetylase sirtuin-7.
  
0.932
SMAX5B_009736
Putative NAD-dependent protein deacetylase sirtuin-3-like.
  
 
0.917
SMAX5B_002327
NAD-dependent protein deacylase; NAD-dependent protein deacylase. Catalyzes the NAD-dependent hydrolysis of acyl groups from lysine residues; Belongs to the sirtuin family. Class II subfamily.
  
 
0.910
SMAX5B_005744
Nicotinamide-nucleotide adenylyltransferase.
   
 0.898
SMAX5B_014437
Nicotinamide-nucleotide adenylyltransferase.
   
 0.898
SMAX5B_021207
Glutamine-dependent NAD(+) synthetase; In the C-terminal section; belongs to the NAD synthetase family.
    
 0.892
SMAX5B_000774
Putative peroxisomal NADH pyrophosphatase NUDT12.
   
 0.889
SMAX5B_002642
Putative NAD kinase.
  
 
 0.880
Your Current Organism:
Scophthalmus maximus
NCBI taxonomy Id: 52904
Other names: Pleuronectes maximus, Psetta maxima, Rhombus maximus, S. maximus, turbot
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