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KAE1 protein (Coprinopsis cinerea) - STRING interaction network
"KAE1" - tRNA N6-adenosine threonylcarbamoyltransferase in Coprinopsis cinerea
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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KAE1tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. KAE1 likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity. The EKC/KEOPS complex also promotes both telomere uncapping and telomere elongation. Th [...] (367 aa)    
Predicted Functional Partners:
CC1G_13096
other/Bud32 protein kinase (259 aa)
   
 
  0.972
CC1G_08235
Uncharacterized protein; Belongs to the CGI121/TPRKB family (200 aa)
     
 
  0.963
CC1G_14619
YwlC protein (471 aa)
   
   
  0.897
CC1G_08103
Thioredoxin (241 aa)
     
 
  0.795
CC1G_04206
Signal recognition particle 54 kDa protein; Binds to the signal sequence of presecretory protein when they emerge from the ribosomes and transfers them to TRAM (translocating chain-associating membrane protein); Belongs to the GTP-binding SRP family. SRP54 subfamily (574 aa)
   
   
  0.738
CC1G_03229
isoleucine-tRNA ligase; Belongs to the class-I aminoacyl-tRNA synthetase family (1078 aa)
   
   
  0.733
CC1G_09322
Uncharacterized protein (594 aa)
       
      0.704
CC1G_09213
Transcriptional activator (162 aa)
       
 
  0.703
CC1G_07407
Autophagy protein 5; Involved in cytoplasm to vacuole transport (Cvt) and autophagic vesicle formation (364 aa)
 
 
        0.696
CC1G_05258
isoleucyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family (1073 aa)
   
   
  0.692
Your Current Organism:
Coprinopsis cinerea
NCBI taxonomy Id: 5346
Other names: C. cinerea, Coprinopsis cinerea, Coprinus cinereus, Coprinus macrorhizus
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