Groups of genes that are frequently observed in each other's genomic neighborhood.
Known metabolic pathways, protein complexes, signal transduction pathways, etc ... from curated databases.
Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
empty nodes: proteins of unknown 3D structure
filled nodes: some 3D structure is known or predicted
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
from curated databases
Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (262 aa)
Predicted Functional Partners:
Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles (1700 aa)
Uncharacterized protein (2084 aa)
ENTH domain-containing protein (963 aa)
Cytoskeleton assembly control protein (1051 aa)
UBA domain-containing protein 7 (815 aa)
Uncharacterized protein (550 aa)
Actin binding protein; Belongs to the actin family (390 aa)
other/NAK protein kinase (1247 aa)
EH domain binding protein epsin 2 (545 aa)
AP-2 complex subunit alpha; Adaptins are components of the adaptor complexes which link clathrin to receptors in coated vesicles. Clathrin-associated protein complexes are believed to interact with the cytoplasmic tails of membrane proteins, leading to their selection and concentration (935 aa)
Your Current Organism:
NCBI taxonomy Id: 5346 Other names: C. cinerea, Coprinopsis cinerea, Coprinus cinereus, Coprinus macrorhizus