STRINGSTRING
GET1 protein (Coprinopsis cinerea) - STRING interaction network
"GET1" - Protein GET1 in Coprinopsis cinerea
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GET1Protein GET1; Required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Acts as a membrane receptor for soluble GET3, which recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol (227 aa)    
Predicted Functional Partners:
GET3
ATPase GET3; ATPase required for the post-translational delivery of tail-anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail- anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. S [...] (326 aa)
     
 
  0.962
CC1G_10037
Cytoplasmic protein (333 aa)
       
 
  0.852
CC1G_04689
HDEL sequence binding protein (189 aa)
           
  0.785
CC1G_03157
Protein transporter; Belongs to the SecY/SEC61-alpha family (477 aa)
       
 
  0.784
CC1G_01785
Integral membrane protein sed5 (337 aa)
       
 
  0.703
CC1G_00017
Protein transporter SEC22; Belongs to the synaptobrevin family (218 aa)
     
 
  0.700
CC1G_07282
Protein transport protein Sec61 subunit beta; Necessary for protein translocation in the endoplasmic reticulum (97 aa)
     
 
  0.686
CC1G_00072
Uncharacterized protein (187 aa)
       
 
  0.680
CC1G_00208
ER membrane protein complex subunit 3; The EMC seems to be required for efficient folding of proteins in the endoplasmic reticulum (ER) (259 aa)
       
 
  0.658
CC1G_10288
Cytoplasmic protein (338 aa)
       
 
  0.656
Your Current Organism:
Coprinopsis cinerea
NCBI taxonomy Id: 5346
Other names: C. cinerea, Coprinopsis cinerea, Coprinus cinereus, Coprinus macrorhizus
Server load: low (18%) [HD]