STRINGSTRING
CC1G_01108 protein (Coprinopsis cinerea) - STRING interaction network
"CC1G_01108" - Cysteine desulfurase NFS1 in Coprinopsis cinerea
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CC1G_01108Cysteine desulfurase NFS1 (477 aa)    
Predicted Functional Partners:
CC1G_01270
Iron-sulfur cluster assembly protein; Scaffold protein for the de novo synthesis of iron- sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins (180 aa)
 
 
  0.989
UBA4
Adenylyltransferase and sulfurtransferase UBA4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Acts by mediating the C-terminal thiocarboxylation of sulfur carrier URM1. Its N-terminus first activates URM1 as acyl- adenylate (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to URM1 to form thiocarboxylation (-COSH) of its C-terminus. The reaction probably involves hydrogen sulfide that is generated from the persulfide intermediate and that acts as nucleophile towards URM1. Subsequ [...] (407 aa)
   
  0.976
CC1G_08652
Thiosulfate sulfurtransferase (329 aa)
     
  0.975
CC1G_08622
Uncharacterized protein (119 aa)
     
 
  0.962
CC1G_11438
Uncharacterized protein; Belongs to the complex I LYR family (102 aa)
     
 
  0.961
CC1G_06716
Uncharacterized protein (234 aa)
 
 
  0.943
CC1G_11859
Adrenodoxin-type ferredoxin (199 aa)
 
 
  0.936
CC1G_03730
NifU-like protein c (291 aa)
   
 
  0.921
CC1G_03726
Iron sulfur assembly protein 1 (218 aa)
   
   
  0.880
CTU1
Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation (344 aa)
   
   
  0.875
Your Current Organism:
Coprinopsis cinerea
NCBI taxonomy Id: 5346
Other names: C. cinerea, Coprinopsis cinerea, Coprinus cinereus, Coprinus macrorhizus
Server load: low (11%) [HD]