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FEN1 protein (Coprinopsis cinerea) - STRING interaction network
"FEN1" - Flap endonuclease 1 in Coprinopsis cinerea
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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FEN1Flap endonuclease 1; Structure-specific nuclease with 5’-flap endonuclease and 5’-3’ exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5’-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5’-end of a downstream Okazaki fragment. It enters the flap from the 5’-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site-terminated flap. Acts as a [...] (422 aa)    
Predicted Functional Partners:
CC1G_05633
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase’s processibility during elongation of the leading strand (368 aa)
     
 
  0.996
CC1G_11289
DNA ligase I (803 aa)
     
 
  0.985
CC1G_01319
DNA helicase; Mis5 protein; Belongs to the MCM family (963 aa)
   
 
  0.976
CC1G_11474
DNA replication helicase dna2 (1482 aa)
   
 
  0.964
CC1G_07448
DNA helicase (1129 aa)
   
 
  0.962
CC1G_07657
DNA mismatch repair protein msh6 (1269 aa)
   
 
  0.960
CC1G_04383
ATP dependent DNA helicase; Belongs to the MCM family (737 aa)
   
 
  0.956
CC1G_05221
DNA mismatch repair protein MSH2; Component of the post-replicative DNA mismatch repair system (MMR) (962 aa)
   
 
  0.952
CC1G_11443
DNA helicase; Cell division control protein 54; Belongs to the MCM family (968 aa)
   
 
  0.950
CC1G_10284
ATP dependent DNA helicase; Belongs to the MCM family (846 aa)
   
 
  0.932
Your Current Organism:
Coprinopsis cinerea
NCBI taxonomy Id: 5346
Other names: C. cinerea, Coprinopsis cinerea, Coprinus cinereus, Coprinus macrorhizus
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