STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
COP4Linoleate 10R-lipoxygenase COP4; Sesquiterpene synthase that catalyzes the cyclization of farnesyl diphosphate (FPP) into multiple products, including germacrene D, beta-copaene, beta-cubebene, (+)-sativene and cubebol, a natural sesquiterpene alcohol used in the food industry for its cooling and refreshing taste. Terpenoid hydrocarbons resulting from cyclization of farnesyl diphosphate are intermediates in the biosynthesis of biologically active compounds such as antibiotics, toxins and pheromones. (345 aa)    
Predicted Functional Partners:
COP6
Alpha-cuprenene synthase COP6; Alpha-cuprenene synthase; part of the gene cluster that mediates the biosynthesis of alpha-cuprenene and oxidized derivatives. The alpha-cuprenene synthase COP6 is the only sesquiterpene synthase identified in C.cinereus that appears to be part of a biosynthetic gene cluster and is highly specific since it catalyzes the cyclization of (2E,6E)-farnesyl diphosphate into only one product, alpha-cuprenene. COP6 is also able to perform the cyclization of geranyl diphosphate. The cytochrome P450 monooxygenase COX2 then oxidizes the cyclohexadiene ring of alpha- [...]
      
 0.485
Your Current Organism:
Coprinopsis cinerea
NCBI taxonomy Id: 240176
Other names: C. cinerea okayama7#130, Coprinopsis cinerea okayama7#130, Coprinus cinereus okayama7#130
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