STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LENED_002636YTH domain-containing protein 1. (664 aa)    
Predicted Functional Partners:
LENED_000430
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.985
LENED_008404
Cleavage and polyadenylation specific protein.
   
 0.982
LENED_008551
Pre-mrna polyadenylation factor fip1.
   
 0.977
LENED_009596
Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...]
   
 0.977
LENED_005417
Cfia complex component.
    
 
 0.948
CLP1
mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.
   
 0.948
LENED_001286
Uncharacterized protein.
    
  0.929
LENED_000341
Pre-mrna cleavage factor cfi subunit.
   
 0.927
LENED_004102
Poly polymerase pla1.
    
 0.924
LENED_010894
Duf455 domain-containing protein.
    
 0.924
Your Current Organism:
Lentinula edodes
NCBI taxonomy Id: 5353
Other names: L. edodes, Lentinus edodes, shiitake mushroom
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.