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CLM_3187 protein (Clostridium botulinum A2 Kyoto) - STRING interaction network
"CLM_3187" - Putative excinuclease ABC, A subunit in Clostridium botulinum A2 Kyoto
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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CLM_3187Putative excinuclease ABC, A subunit; Identified by match to protein family HMM PF00005 (752 aa)    
Predicted Functional Partners:
uvrB
UvrABC system protein B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and [...] (662 aa)
 
 
  0.900
CLM_3186
Transcriptional regulator, MarR family; Identified by match to protein family HMM PF01047; match to protein family HMM PF03965 (139 aa)
 
          0.881
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5’-3’ exonuclease activity (875 aa)
 
   
  0.772
CLM_3616
GIY-YIG domain protein; Identified by match to protein family HMM PF01541 (365 aa)
 
 
  0.746
uvrC
UvrABC system protein C; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5’ and 3’ sides of the lesion. The N-terminal half is responsible for the 3’ incision and the C-terminal half is responsible for the 5’ incision (618 aa)
 
 
  0.668
mfd
Transcription-repair-coupling factor; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site (1168 aa)
   
 
  0.647
CLM_1055
Putative LexA repressor; Identified by match to protein family HMM PF00717; match to protein family HMM TIGR00498; Belongs to the peptidase S24 family (531 aa)
   
 
  0.580
dnaJ
Chaperone protein DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, D [...] (381 aa)
   
 
  0.529
pcrA
ATP-dependent DNA helicase; Identified by match to protein family HMM PF00580 (738 aa)
 
 
  0.499
ftsZ
Cell division protein FtsZ; Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity (369 aa)
       
 
  0.460
Your Current Organism:
Clostridium botulinum A2 Kyoto
NCBI taxonomy Id: 536232
Other names: C. botulinum A2 str. Kyoto, Clostridium botulinum A2 Kyoto, Clostridium botulinum A2 str. Kyoto, Clostridium botulinum A2 strain Kyoto
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