node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFD58990.1 | SFD65708.1 | SAMN02745121_00767 | SAMN02745121_00967 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Heterodimeric methylmalonyl-CoA mutase small subunit. | 0.874 |
SFD58990.1 | SFD65717.1 | SAMN02745121_00767 | SAMN02745121_00968 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | 0.874 |
SFD58990.1 | SFD94547.1 | SAMN02745121_00767 | SAMN02745121_02358 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Acyl-CoA hydrolase. | 0.687 |
SFD58990.1 | SFE07641.1 | SAMN02745121_00767 | SAMN02745121_02915 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | 0.889 |
SFD58990.1 | SFE72185.1 | SAMN02745121_00767 | SAMN02745121_05277 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Citrate synthase. | 0.858 |
SFD58990.1 | SFE98211.1 | SAMN02745121_00767 | SAMN02745121_06359 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | propionyl-CoA carboxylase carboxyltransferase subunit. | 0.912 |
SFD58990.1 | icmF | SAMN02745121_00767 | SAMN02745121_00620 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.884 |
SFD58990.1 | mdh | SAMN02745121_00767 | SAMN02745121_07784 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.867 |
SFD58990.1 | sucD | SAMN02745121_00767 | SAMN02745121_07782 | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.666 |
SFD65708.1 | SFD58990.1 | SAMN02745121_00967 | SAMN02745121_00767 | Heterodimeric methylmalonyl-CoA mutase small subunit. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.874 |
SFD65708.1 | SFD65717.1 | SAMN02745121_00967 | SAMN02745121_00968 | Heterodimeric methylmalonyl-CoA mutase small subunit. | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | 0.999 |
SFD65708.1 | SFD94547.1 | SAMN02745121_00967 | SAMN02745121_02358 | Heterodimeric methylmalonyl-CoA mutase small subunit. | Acyl-CoA hydrolase. | 0.935 |
SFD65708.1 | SFE07641.1 | SAMN02745121_00967 | SAMN02745121_02915 | Heterodimeric methylmalonyl-CoA mutase small subunit. | 2-oxoglutarate ferredoxin oxidoreductase subunit alpha. | 0.902 |
SFD65708.1 | SFE72185.1 | SAMN02745121_00967 | SAMN02745121_05277 | Heterodimeric methylmalonyl-CoA mutase small subunit. | Citrate synthase. | 0.866 |
SFD65708.1 | SFE98211.1 | SAMN02745121_00967 | SAMN02745121_06359 | Heterodimeric methylmalonyl-CoA mutase small subunit. | propionyl-CoA carboxylase carboxyltransferase subunit. | 0.925 |
SFD65708.1 | SFF25394.1 | SAMN02745121_00967 | SAMN02745121_07742 | Heterodimeric methylmalonyl-CoA mutase small subunit. | methylmalonyl-CoA mutase metallochaperone MeaB. | 0.982 |
SFD65708.1 | icmF | SAMN02745121_00967 | SAMN02745121_00620 | Heterodimeric methylmalonyl-CoA mutase small subunit. | methylmalonyl-CoA mutase; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.999 |
SFD65708.1 | mdh | SAMN02745121_00967 | SAMN02745121_07784 | Heterodimeric methylmalonyl-CoA mutase small subunit. | Malate dehydrogenase (NAD); Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.864 |
SFD65708.1 | sucD | SAMN02745121_00967 | SAMN02745121_07782 | Heterodimeric methylmalonyl-CoA mutase small subunit. | succinyl-CoA synthetase (ADP-forming) alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.872 |
SFD65717.1 | SFD58990.1 | SAMN02745121_00968 | SAMN02745121_00767 | Heterodimeric methylmalonyl-CoA mutase large subunit precursor. | Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. | 0.874 |