node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SFD59517.1 | SFD64669.1 | SAMN02745121_00795 | SAMN02745121_00892 | Monothiol glutaredoxin. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.808 |
SFD59517.1 | SFE33360.1 | SAMN02745121_00795 | SAMN02745121_03878 | Monothiol glutaredoxin. | Glutaredoxin. | 0.803 |
SFD59517.1 | SFE62271.1 | SAMN02745121_00795 | SAMN02745121_04913 | Monothiol glutaredoxin. | Monothiol glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.929 |
SFD59517.1 | msrA-2 | SAMN02745121_00795 | SAMN02745121_05101 | Monothiol glutaredoxin. | methionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.563 |
SFD59517.1 | msrB | SAMN02745121_00795 | SAMN02745121_08329 | Monothiol glutaredoxin. | Peptide-methionine (R)-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family. | 0.563 |
SFD64669.1 | SFD59517.1 | SAMN02745121_00892 | SAMN02745121_00795 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Monothiol glutaredoxin. | 0.808 |
SFD64669.1 | SFE00661.1 | SAMN02745121_00892 | SAMN02745121_02641 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.426 |
SFD64669.1 | SFE33360.1 | SAMN02745121_00892 | SAMN02745121_03878 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Glutaredoxin. | 0.822 |
SFD64669.1 | SFE59462.1 | SAMN02745121_00892 | SAMN02745121_04776 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.426 |
SFD64669.1 | SFE62271.1 | SAMN02745121_00892 | SAMN02745121_04913 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Monothiol glutaredoxin; Belongs to the glutaredoxin family. Monothiol subfamily. | 0.808 |
SFD64669.1 | SFE97902.1 | SAMN02745121_00892 | SAMN02745121_06340 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PAS domain S-box-containing protein. | 0.539 |
SFD64669.1 | msrA-2 | SAMN02745121_00892 | SAMN02745121_05101 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | methionine-S-sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.574 |
SFD64669.1 | msrB | SAMN02745121_00892 | SAMN02745121_08329 | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Peptide-methionine (R)-S-oxide reductase; Belongs to the MsrB Met sulfoxide reductase family. | 0.574 |
SFE00661.1 | SFD64669.1 | SAMN02745121_02641 | SAMN02745121_00892 | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.426 |
SFE00661.1 | SFE33360.1 | SAMN02745121_02641 | SAMN02745121_03878 | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | Glutaredoxin. | 0.916 |
SFE00661.1 | ribB | SAMN02745121_02641 | SAMN02745121_07190 | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | GTP cyclohydrolase II /3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; Belongs to the DHBP synthase family. | 0.835 |
SFE33360.1 | SFD59517.1 | SAMN02745121_03878 | SAMN02745121_00795 | Glutaredoxin. | Monothiol glutaredoxin. | 0.803 |
SFE33360.1 | SFD64669.1 | SAMN02745121_03878 | SAMN02745121_00892 | Glutaredoxin. | Methionine synthase (B12-dependent); Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.822 |
SFE33360.1 | SFE00661.1 | SAMN02745121_03878 | SAMN02745121_02641 | Glutaredoxin. | Ribonucleoside-diphosphate reductase class II; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen. | 0.916 |
SFE33360.1 | SFE59462.1 | SAMN02745121_03878 | SAMN02745121_04776 | Glutaredoxin. | Ribonucleoside-diphosphate reductase alpha chain; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.916 |