STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
addAdenosine deaminase; KEGG: hdu:HD0377 1.4e-63 add; probable adenosine deaminase K01488; Psort location: Cytoplasmic, score: 8.87. (350 aa)    
Predicted Functional Partners:
apt
Adenine phosphoribosyltransferase; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
  
 0.941
deoD
KEGG: ftl:FTL_1461 2.9e-63 purine nucleoside phosphorylase K03784; Psort location: Cytoplasmic, score: 8.87.
    
 0.870
EEF66225.1
KEGG: lin:lin0179 4.2e-220 similar to inosine monophosphate dehydrogenase K00088; Psort location: Cytoplasmic, score: 8.87.
  
 0.846
EEF66813.1
KEGG: bce:BC0896 2.4e-20 S-layer protein / peptidoglycan endo-beta-N-acetylglucosaminidase K01238.
    
  0.828
EEF69644.1
DNA-binding helix-turn-helix protein; Psort location: Cellwall, score: 9.25.
 
 
 0.826
EEF69761.1
KEGG: lin:lin1782 2.2e-05 hypothetical protein K08680; Psort location: Cytoplasmic, score: 8.87.
  
 
 0.811
purA
Adenylosuccinate synthase; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
  
 
 0.804
EEF67932.1
PP-loop family protein; KEGG: nme:NMB1023 2.4e-27 hypothetical protein K04075; Psort location: Cytoplasmic, score: 8.87; Belongs to the TtcA family.
 
 
 0.802
EEF67996.1
KEGG: lsa:LSA0533 3.7e-70 iunH2; inosine-uridine preferring nucleoside hydrolase K01239; Psort location: Cytoplasmic, score: 8.87.
 
 
 0.791
hpt
Hypoxanthine phosphoribosyltransferase; KEGG: lla:L25115 1.4e-52 hpt; hypoxantine-guanine phosphorybosyltransferase K00760; Psort location: Cytoplasmic, score: 9.98; Belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
  
 0.790
Your Current Organism:
Holdemania filiformis
NCBI taxonomy Id: 545696
Other names: H. filiformis DSM 12042, Holdemania filiformis DSM 12042, Holdemania filiformis str. DSM 12042, Holdemania filiformis strain DSM 12042
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.