node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACO45652.1 | pdxH | Deide_07880 | Deide_06601 | Putative oxidoreductase. | Putative pyridoxal 5-phosphate synthase (pyridoxamine 5-phosphate oxidase); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.900 |
ACO45652.1 | pdxY | Deide_07880 | Deide_01840 | Putative oxidoreductase. | Putative Pyridoxamine kinase (PM kinase); Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.900 |
ACO46809.1 | gcvP | Deide_18220 | Deide_04940 | Putative anthranilate synthase (Glutamine amidotransferase of anthranilate synthase). | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.426 |
ACO46809.1 | pdxH | Deide_18220 | Deide_06601 | Putative anthranilate synthase (Glutamine amidotransferase of anthranilate synthase). | Putative pyridoxal 5-phosphate synthase (pyridoxamine 5-phosphate oxidase); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.412 |
gcvP | ACO46809.1 | Deide_04940 | Deide_18220 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Putative anthranilate synthase (Glutamine amidotransferase of anthranilate synthase). | 0.426 |
gcvP | pdxH | Deide_04940 | Deide_06601 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Putative pyridoxal 5-phosphate synthase (pyridoxamine 5-phosphate oxidase); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.514 |
mutM | pcp | Deide_16240 | Deide_16250 | Putative formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Pyroglutamyl-peptidase I; Removes 5-oxoproline from various penultimate amino acid residues except L-proline. | 0.731 |
mutM | pdxH | Deide_16240 | Deide_06601 | Putative formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Putative pyridoxal 5-phosphate synthase (pyridoxamine 5-phosphate oxidase); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.469 |
pcp | mutM | Deide_16250 | Deide_16240 | Pyroglutamyl-peptidase I; Removes 5-oxoproline from various penultimate amino acid residues except L-proline. | Putative formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.731 |
pcp | pdxH | Deide_16250 | Deide_06601 | Pyroglutamyl-peptidase I; Removes 5-oxoproline from various penultimate amino acid residues except L-proline. | Putative pyridoxal 5-phosphate synthase (pyridoxamine 5-phosphate oxidase); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | 0.431 |
pdxH | ACO45652.1 | Deide_06601 | Deide_07880 | Putative pyridoxal 5-phosphate synthase (pyridoxamine 5-phosphate oxidase); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Putative oxidoreductase. | 0.900 |
pdxH | ACO46809.1 | Deide_06601 | Deide_18220 | Putative pyridoxal 5-phosphate synthase (pyridoxamine 5-phosphate oxidase); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Putative anthranilate synthase (Glutamine amidotransferase of anthranilate synthase). | 0.412 |
pdxH | gcvP | Deide_06601 | Deide_04940 | Putative pyridoxal 5-phosphate synthase (pyridoxamine 5-phosphate oxidase); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.514 |
pdxH | mutM | Deide_06601 | Deide_16240 | Putative pyridoxal 5-phosphate synthase (pyridoxamine 5-phosphate oxidase); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Putative formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.469 |
pdxH | pcp | Deide_06601 | Deide_16250 | Putative pyridoxal 5-phosphate synthase (pyridoxamine 5-phosphate oxidase); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Pyroglutamyl-peptidase I; Removes 5-oxoproline from various penultimate amino acid residues except L-proline. | 0.431 |
pdxH | pdxS | Deide_06601 | Deide_11610 | Putative pyridoxal 5-phosphate synthase (pyridoxamine 5-phosphate oxidase); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Putative pyridoxine biosynthesis enzyme; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family. | 0.922 |
pdxH | pdxT | Deide_06601 | Deide_11600 | Putative pyridoxal 5-phosphate synthase (pyridoxamine 5-phosphate oxidase); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Putative glutamine amidotransferase; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS. | 0.927 |
pdxH | pdxY | Deide_06601 | Deide_01840 | Putative pyridoxal 5-phosphate synthase (pyridoxamine 5-phosphate oxidase); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Putative Pyridoxamine kinase (PM kinase); Pyridoxal kinase involved in the salvage pathway of pyridoxal 5'-phosphate (PLP). Catalyzes the phosphorylation of pyridoxal to PLP. | 0.935 |
pdxH | pyrB | Deide_06601 | Deide_18110 | Putative pyridoxal 5-phosphate synthase (pyridoxamine 5-phosphate oxidase); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Putative aspartate carbamoyltransferase (Aspartate transcarbamylase); Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.576 |
pdxH | ribAB | Deide_06601 | Deide_02250 | Putative pyridoxal 5-phosphate synthase (pyridoxamine 5-phosphate oxidase); Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). | Putative Riboflavin biosynthesis protein ribBA; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. | 0.443 |