node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACO46271.1 | ACO46362.1 | Deide_13330 | Deide_14150 | Putative 5'-nucleotidase (UshA), precursor; Belongs to the 5'-nucleotidase family. | Putative Hypoxanthine phosphoribosyltransferase (Hypoxanthine-guanine phosphoribosyltransferase)(HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.903 |
ACO46271.1 | ACO46932.2 | Deide_13330 | Deide_19360 | Putative 5'-nucleotidase (UshA), precursor; Belongs to the 5'-nucleotidase family. | Putative Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.901 |
ACO46271.1 | guaA | Deide_13330 | Deide_05580 | Putative 5'-nucleotidase (UshA), precursor; Belongs to the 5'-nucleotidase family. | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.916 |
ACO46271.1 | guaB | Deide_13330 | Deide_06210 | Putative 5'-nucleotidase (UshA), precursor; Belongs to the 5'-nucleotidase family. | Putative Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.908 |
ACO46271.1 | surE | Deide_13330 | Deide_22950 | Putative 5'-nucleotidase (UshA), precursor; Belongs to the 5'-nucleotidase family. | Putative multifunctional protein (stationary phase survival protein); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.909 |
ACO46271.1 | xpt | Deide_13330 | Deide_04030 | Putative 5'-nucleotidase (UshA), precursor; Belongs to the 5'-nucleotidase family. | Putative Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.906 |
ACO46362.1 | ACO46271.1 | Deide_14150 | Deide_13330 | Putative Hypoxanthine phosphoribosyltransferase (Hypoxanthine-guanine phosphoribosyltransferase)(HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Putative 5'-nucleotidase (UshA), precursor; Belongs to the 5'-nucleotidase family. | 0.903 |
ACO46362.1 | ACO46932.2 | Deide_14150 | Deide_19360 | Putative Hypoxanthine phosphoribosyltransferase (Hypoxanthine-guanine phosphoribosyltransferase)(HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Putative Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.908 |
ACO46362.1 | guaA | Deide_14150 | Deide_05580 | Putative Hypoxanthine phosphoribosyltransferase (Hypoxanthine-guanine phosphoribosyltransferase)(HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.956 |
ACO46362.1 | guaB | Deide_14150 | Deide_06210 | Putative Hypoxanthine phosphoribosyltransferase (Hypoxanthine-guanine phosphoribosyltransferase)(HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Putative Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.927 |
ACO46362.1 | surE | Deide_14150 | Deide_22950 | Putative Hypoxanthine phosphoribosyltransferase (Hypoxanthine-guanine phosphoribosyltransferase)(HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Putative multifunctional protein (stationary phase survival protein); Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
ACO46362.1 | xpt | Deide_14150 | Deide_04030 | Putative Hypoxanthine phosphoribosyltransferase (Hypoxanthine-guanine phosphoribosyltransferase)(HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. | Putative Xanthine phosphoribosyltransferase; Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis. | 0.918 |
ACO46932.2 | ACO46271.1 | Deide_19360 | Deide_13330 | Putative Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative 5'-nucleotidase (UshA), precursor; Belongs to the 5'-nucleotidase family. | 0.901 |
ACO46932.2 | ACO46362.1 | Deide_19360 | Deide_14150 | Putative Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative Hypoxanthine phosphoribosyltransferase (Hypoxanthine-guanine phosphoribosyltransferase)(HGPRTase); Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.908 |
ACO46932.2 | ACO47301.1 | Deide_19360 | Deide_22700 | Putative Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative Coproporphyrinogen dehydrogenase (Oxygen-independent coproporphyrinogen-III oxidase); Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine. Belongs to the anaerobic coproporphyrinogen-III oxidase family. | 0.645 |
ACO46932.2 | guaA | Deide_19360 | Deide_05580 | Putative Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative GMP synthase; Catalyzes the synthesis of GMP from XMP. | 0.966 |
ACO46932.2 | guaB | Deide_19360 | Deide_06210 | Putative Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.932 |
ACO46932.2 | murI | Deide_19360 | Deide_22090 | Putative Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.915 |
ACO46932.2 | ndk | Deide_19360 | Deide_07830 | Putative Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative nucleoside-diphosphate kinase (Nucleoside-2-P kinase); Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.931 |
ACO46932.2 | rph | Deide_19360 | Deide_22100 | Putative Non-canonical purine NTP pyrophosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Putative tRNA nucleotidyltransferase (Phosphate-dependent exonuclease) (Ribonuclease PH) (RNase PH); Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.957 |