node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Mmah_0334 | Mmah_0746 | Mmah_0334 | Mmah_0746 | COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: dde:Dde_0551 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Q12U61 Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: cbc:CbuK_0042 ATP-dependent DNA ligase; SPTR: Q8Q0C8 Putative uncharacterized protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | 0.652 |
Mmah_0334 | Mmah_1090 | Mmah_0334 | Mmah_1090 | COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: dde:Dde_0551 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Q12U61 Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | PHP domain protein; COGs: COG1796 DNA polymerase IV (family X); InterProIPR002008:IPR004013:IPR002054:IPR003141:IPR 003583; KEGG: cbc:CbuK_1370 DNA polymerase X family; PFAM: PHP domain protein; SMART: DNA polymerase X; phosphoesterase PHP domain protein; Helix-hairpin-helix DNA-binding class 1; SPTR: Q46C05 DNA polymerase X family / putative histidinol phosphatase; PFAM: PHP domain. | 0.999 |
Mmah_0334 | Mmah_1995 | Mmah_0334 | Mmah_1995 | COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: dde:Dde_0551 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Q12U61 Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | COGs: COG0417 DNA polymerase elongation subunit (family B); InterProIPR017966:IPR006134:IPR006133:IPR006172:IPR 017964:IPR004578; KEGG: CaJ7_0319; hypothetical protein; K02327 DNA polymerase delta subunit 1; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: DNA-directed DNA polymerase B; SPTR: Q12VE4 DNA polymerase; TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; TIGRFAM: DNA polymerase (pol2). | 0.775 |
Mmah_0334 | fen | Mmah_0334 | Mmah_1845 | COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: dde:Dde_0551 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Q12U61 Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.999 |
Mmah_0334 | lig | Mmah_0334 | Mmah_0567 | COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: dde:Dde_0551 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Q12U61 Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.652 |
Mmah_0334 | lig-2 | Mmah_0334 | Mmah_1091 | COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: dde:Dde_0551 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Q12U61 Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.652 |
Mmah_0334 | pcn | Mmah_0334 | Mmah_0388 | COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: dde:Dde_0551 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Q12U61 Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | Monomeric archaeal DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.943 |
Mmah_0334 | polB | Mmah_0334 | Mmah_0003 | COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: dde:Dde_0551 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Q12U61 Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. | 0.710 |
Mmah_0746 | Mmah_0334 | Mmah_0746 | Mmah_0334 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: cbc:CbuK_0042 ATP-dependent DNA ligase; SPTR: Q8Q0C8 Putative uncharacterized protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: dde:Dde_0551 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Q12U61 Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | 0.652 |
Mmah_0746 | Mmah_0747 | Mmah_0746 | Mmah_0747 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: cbc:CbuK_0042 ATP-dependent DNA ligase; SPTR: Q8Q0C8 Putative uncharacterized protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | Polyphosphate:AMP phosphotransferase; COGs: COG2326 conserved hypothetical protein; InterPro IPR005660; KEGG: hha:Hhal_1873 hypothetical protein; PFAM: protein of unknown function DUF344; SPTR: Q8TNA2 Putative uncharacterized protein; PFAM: Polyphosphate kinase 2 (PPK2). | 0.571 |
Mmah_0746 | Mmah_1090 | Mmah_0746 | Mmah_1090 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: cbc:CbuK_0042 ATP-dependent DNA ligase; SPTR: Q8Q0C8 Putative uncharacterized protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | PHP domain protein; COGs: COG1796 DNA polymerase IV (family X); InterProIPR002008:IPR004013:IPR002054:IPR003141:IPR 003583; KEGG: cbc:CbuK_1370 DNA polymerase X family; PFAM: PHP domain protein; SMART: DNA polymerase X; phosphoesterase PHP domain protein; Helix-hairpin-helix DNA-binding class 1; SPTR: Q46C05 DNA polymerase X family / putative histidinol phosphatase; PFAM: PHP domain. | 0.843 |
Mmah_0746 | Mmah_1995 | Mmah_0746 | Mmah_1995 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: cbc:CbuK_0042 ATP-dependent DNA ligase; SPTR: Q8Q0C8 Putative uncharacterized protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | COGs: COG0417 DNA polymerase elongation subunit (family B); InterProIPR017966:IPR006134:IPR006133:IPR006172:IPR 017964:IPR004578; KEGG: CaJ7_0319; hypothetical protein; K02327 DNA polymerase delta subunit 1; PFAM: DNA polymerase B region; DNA polymerase B exonuclease; PRIAM: DNA-directed DNA polymerase; SMART: DNA-directed DNA polymerase B; SPTR: Q12VE4 DNA polymerase; TIGRFAM: DNA polymerase Pol2; PFAM: DNA polymerase family B; DNA polymerase family B, exonuclease domain; TIGRFAM: DNA polymerase (pol2). | 0.698 |
Mmah_0746 | fen | Mmah_0746 | Mmah_1845 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: cbc:CbuK_0042 ATP-dependent DNA ligase; SPTR: Q8Q0C8 Putative uncharacterized protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) pathway. A [...] | 0.822 |
Mmah_0746 | lig | Mmah_0746 | Mmah_0567 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: cbc:CbuK_0042 ATP-dependent DNA ligase; SPTR: Q8Q0C8 Putative uncharacterized protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.919 |
Mmah_0746 | lig-2 | Mmah_0746 | Mmah_1091 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: cbc:CbuK_0042 ATP-dependent DNA ligase; SPTR: Q8Q0C8 Putative uncharacterized protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | DNA ligase I, ATP-dependent Dnl1; DNA ligase that seals nicks in double-stranded DNA during DNA replication, DNA recombination and DNA repair. | 0.943 |
Mmah_0746 | mre11 | Mmah_0746 | Mmah_1807 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: cbc:CbuK_0042 ATP-dependent DNA ligase; SPTR: Q8Q0C8 Putative uncharacterized protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | Metallophosphoesterase; Part of the Rad50/Mre11 complex, which is involved in the early steps of DNA double-strand break (DSB) repair. The complex may facilitate opening of the processed DNA ends to aid in the recruitment of HerA and NurA. Mre11 binds to DSB ends and has both double-stranded 3'-5' exonuclease activity and single-stranded endonuclease activity. Belongs to the MRE11/RAD32 family. | 0.515 |
Mmah_0746 | pcn | Mmah_0746 | Mmah_0388 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: cbc:CbuK_0042 ATP-dependent DNA ligase; SPTR: Q8Q0C8 Putative uncharacterized protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | Monomeric archaeal DNA polymerase sliding clamp; Sliding clamp subunit that acts as a moving platform for DNA processing. Responsible for tethering the catalytic subunit of DNA polymerase and other proteins to DNA during high-speed replication. | 0.909 |
Mmah_0746 | polB | Mmah_0746 | Mmah_0003 | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: cbc:CbuK_0042 ATP-dependent DNA ligase; SPTR: Q8Q0C8 Putative uncharacterized protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | DNA-directed DNA polymerase; Possesses two activities: a DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3' to 5' direction. Has a template-primer preference which is characteristic of a replicative DNA polymerase; Belongs to the DNA polymerase delta/II small subunit family. | 0.531 |
Mmah_0747 | Mmah_0746 | Mmah_0747 | Mmah_0746 | Polyphosphate:AMP phosphotransferase; COGs: COG2326 conserved hypothetical protein; InterPro IPR005660; KEGG: hha:Hhal_1873 hypothetical protein; PFAM: protein of unknown function DUF344; SPTR: Q8TNA2 Putative uncharacterized protein; PFAM: Polyphosphate kinase 2 (PPK2). | DNA ligase D, 3'-phosphoesterase domain protein; InterPro IPR014144; KEGG: cbc:CbuK_0042 ATP-dependent DNA ligase; SPTR: Q8Q0C8 Putative uncharacterized protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain protein; TIGRFAM: DNA ligase D, 3'-phosphoesterase domain. | 0.571 |
Mmah_1090 | Mmah_0334 | Mmah_1090 | Mmah_0334 | PHP domain protein; COGs: COG1796 DNA polymerase IV (family X); InterProIPR002008:IPR004013:IPR002054:IPR003141:IPR 003583; KEGG: cbc:CbuK_1370 DNA polymerase X family; PFAM: PHP domain protein; SMART: DNA polymerase X; phosphoesterase PHP domain protein; Helix-hairpin-helix DNA-binding class 1; SPTR: Q46C05 DNA polymerase X family / putative histidinol phosphatase; PFAM: PHP domain. | COGs: COG0708 Exonuclease III; InterPro IPR005135:IPR000097:IPR004808; KEGG: dde:Dde_0551 exodeoxyribonuclease III; PFAM: Endonuclease/exonuclease/phosphatase; PRIAM: DNA-(apurinic or apyrimidinic site) lyase; SPTR: Q12U61 Exodeoxyribonuclease III; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/Exonuclease/phosphatase family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III (xth). | 0.999 |