STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lysSCOGs: COG1384 Lysyl-tRNA synthetase (class I); InterPro IPR002904:IPR001412; KEGG: noc:Noc_1618 lysine--tRNA ligase; PFAM: Lysyl-tRNA synthetase class 1c; PRIAM: Lysine--tRNA ligase; SPTR: Q12UX8 Lysyl-tRNA synthetase; TIGRFAM: lysyl-tRNA synthetase; PFAM: tRNA synthetases class I (K); TIGRFAM: lysyl-tRNA synthetase, archaeal and spirochete; Belongs to the class-I aminoacyl-tRNA synthetase family. (527 aa)    
Predicted Functional Partners:
Mmah_1892
Methyltransferase type 11; COGs: COG2226 Methylase involved in ubiquinone/menaquinone biosynthesis; InterPro IPR013216:IPR013217; KEGG: Methyltransferase-like protein; PFAM: Methyltransferase type 11; Methyltransferase type 12; SPTR: Q12UX9 Putative uncharacterized protein; PFAM: Methyltransferase domain.
       0.799
spt5
LSU ribosomal protein L24A; Stimulates transcription elongation; Belongs to the archaeal Spt5 family.
  
    0.604
Mmah_1322
Peptidase M50; InterPro IPR001193:IPR008915:IPR001478:IPR006025; KEGG: pay:PAU_00651 metalloendopeptidase-protease ecfe; PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein; SPTR: Q12Z71 Peptidase M50; PFAM: Peptidase family M50; PDZ domain (Also known as DHR or GLGF).
       0.582
serS
seryl-tRNA synthetase; Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L- seryl-tRNA(Sec), which will be further converted into selenocysteinyl- tRNA(Sec); Belongs to the class-II aminoacyl-tRNA synthetase family. Type-2 seryl-tRNA synthetase subfamily.
 
  
 0.561
pdaD
Arginine decarboxylase; COGs: COG1945 conserved hypothetical protein; InterPro IPR002724; KEGG: dal:Dalk_3766 arginine decarboxylase, pyruvoyl-dependent; PFAM: Pyruvoyl-dependent arginine decarboxylase; PRIAM: Arginine decarboxylase; SPTR: P58890 Pyruvoyl-dependent arginine decarboxylase 2; TIGRFAM: arginine decarboxylase, pyruvoyl-dependent; PFAM: Pyruvoyl-dependent arginine decarboxylase (PvlArgDC); TIGRFAM: arginine decarboxylase, pyruvoyl-dependent; Belongs to the PdaD family.
       0.551
tyrS
tyrosyl-tRNA synthetase; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 3 subfamily.
   
  
 0.452
leuS
COGs: COG0495 Leucyl-tRNA synthetase; InterProIPR015413:IPR002300:IPR013155:IPR001412:IPR 004493; KEGG: leucyl-tRNA synthetase; K01869 leucyl-tRNA synthetase; PFAM: tRNA synthetase valyl/leucyl anticodon-binding; aminoacyl-tRNA synthetase class Ia; tRNA synthetase class I (M); SPTR: Q12WA2 Leucyl-tRNA synthetase; TIGRFAM: leucyl-tRNA synthetase; PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, archaeal and cytosolic family.
   
 
 0.419
rps4
SSU ribosomal protein S4P; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.
  
  
 0.417
rpl18e
COGs: COG1727 Ribosomal protein L18E; InterPro IPR001196:IPR000039; KEGG: hypothetical protein; K02883 large subunit ribosomal protein L18e; PFAM: ribosomal protein L15; SPTR: Q12TI7 LSU ribosomal protein L18AE; PFAM: Ribosomal protein L18e/L15; Belongs to the eukaryotic ribosomal protein eL18 family.
  
    0.401
Your Current Organism:
Methanohalophilus mahii
NCBI taxonomy Id: 547558
Other names: M. mahii DSM 5219, Methanohalophilus mahii DSM 5219, Methanohalophilus mahii str. DSM 5219, Methanohalophilus mahii strain DSM 5219
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