STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HEM15-aminolevulinate synthase, mitochondrial; Catalyzes the synthesis of 5-aminolevulinate (ALA) from succinyl-CoA and glycine, the first and rate-limiting step in heme biosynthesis; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. (530 aa)    
Predicted Functional Partners:
HEM2
Delta-aminolevulinic acid dehydratase; Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).
  
 
 0.981
Q6FR31_CANGA
Beta_elim_lyase domain-containing protein.
   
 
 0.927
Q6FLV2_CANGA
Glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine.
  
 
 0.926
SHM1
Serine hydroxymethyltransferase, mitochondrial; Interconversion of serine and glycine.
  
 
 0.922
SHM2
Serine hydroxymethyltransferase, cytosolic; Interconversion of serine and glycine; Belongs to the SHMT family.
  
 
 0.922
Q6FLY4_CANGA
Aminotran_5 domain-containing protein.
    
 0.919
Q6FWH2_CANGA
Uncharacterized protein.
  
 
 0.794
ARG8
Acetylornithine aminotransferase, mitochondrial; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.
   
 0.759
Q6FUV9_CANGA
Glutamine amidotransferase type-1 domain-containing protein.
  
  
 0.731
Q6FTQ4_CANGA
3Beta_HSD domain-containing protein.
  
 
 0.699
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, [. glabrata CBS 138, [Candida] glabrata CBS 138
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