node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
CYS4 | NCP1 | Q6FVB8 | Q6FVZ9 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.726 |
CYS4 | Q6FK83_CANGA | Q6FVB8 | Q6FK83 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Flavodoxin-like domain-containing protein. | 0.884 |
CYS4 | Q6FLM3_CANGA | Q6FVB8 | Q6FLM3 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.693 |
CYS4 | Q6FQ76_CANGA | Q6FVB8 | Q6FQ76 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | PAPS_reduct domain-containing protein. | 0.533 |
CYS4 | Q6FTU3_CANGA | Q6FVB8 | Q6FTU3 | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | PALP domain-containing protein. | 0.827 |
DRE2 | NCP1 | Q6FTJ8 | Q6FVZ9 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.750 |
DRE2 | Q6FSG7_CANGA | Q6FTJ8 | Q6FSG7 | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | 2Fe-2S ferredoxin-type domain-containing protein. | 0.419 |
ERG11 | NCP1 | P50859 | Q6FVZ9 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 0.724 |
ERG11 | Q6FLF4_CANGA | P50859 | Q6FLF4 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | 0.849 |
ERG11 | Q6FSG7_CANGA | P50859 | Q6FSG7 | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | 2Fe-2S ferredoxin-type domain-containing protein. | 0.530 |
NCP1 | CYS4 | Q6FVZ9 | Q6FVB8 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | 0.726 |
NCP1 | DRE2 | Q6FVZ9 | Q6FTJ8 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Fe-S cluster assembly protein DRE2; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex CFD1-NBP35. Electrons are transferred to DRE2 from NADPH via the FAD- and FMN-containing protein TAH18. TAH18-DRE2 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by [...] | 0.750 |
NCP1 | ERG11 | Q6FVZ9 | P50859 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Lanosterol 14-alpha demethylase; Catalyzes C14-demethylation of lanosterol which is critical for ergosterol biosynthesis. It transforms lanosterol into 4,4'- dimethyl cholesta-8,14,24-triene-3-beta-ol (By similarity). | 0.724 |
NCP1 | Q6FK83_CANGA | Q6FVZ9 | Q6FK83 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Flavodoxin-like domain-containing protein. | 0.941 |
NCP1 | Q6FLF4_CANGA | Q6FVZ9 | Q6FLF4 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Cytochrome b5 heme-binding domain-containing protein; Belongs to the cytochrome b5 family. | 0.772 |
NCP1 | Q6FLM3_CANGA | Q6FVZ9 | Q6FLM3 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.799 |
NCP1 | Q6FQ76_CANGA | Q6FVZ9 | Q6FQ76 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | PAPS_reduct domain-containing protein. | 0.714 |
NCP1 | Q6FSG7_CANGA | Q6FVZ9 | Q6FSG7 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | 2Fe-2S ferredoxin-type domain-containing protein. | 0.693 |
NCP1 | Q6FTU3_CANGA | Q6FVZ9 | Q6FTU3 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | PALP domain-containing protein. | 0.686 |
NCP1 | Q6FXU4_CANGA | Q6FVZ9 | Q6FXU4 | NADPH--cytochrome P450 reductase; This enzyme is required for electron transfer from NADP to cytochrome P450 in microsomes. It can also provide electron transfer to heme oxygenase and cytochrome B5. Involved in ergosterol biosynthesis. In the C-terminal section; belongs to the flavoprotein pyridine nucleotide cytochrome reductase family. | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. | 0.709 |