STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ICL1Isocitrate lyase; Catalyzes the formation of succinate and glyoxylate from isocitrate, a key step of the glyoxylate cycle, which operates as an anaplerotic route for replenishing the tricarboxylic acid cycle. Required for growth on ethanol or acetate, but dispensable when fermentable carbon sources are available. Acts also on 2- methylisocitrate. (553 aa)    
Predicted Functional Partners:
Q6FLE7_CANGA
Malate synthase; Belongs to the malate synthase family.
 
 
 0.999
ACO1
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.981
Q6FLY4_CANGA
Aminotran_5 domain-containing protein.
  
 
 0.959
Q6FP30_CANGA
2-Hacid_dh_C domain-containing protein.
  
 0.917
Q6FNX6_CANGA
Uncharacterized protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 0.916
Q6FKR5_CANGA
Isocitrate lyase.
  
 
 
0.911
PCK1
Phosphoenolpyruvate carboxykinase (ATP); Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
   
  
 0.891
ACS1
Acetyl-coenzyme A synthetase 1; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.867
ACO2
Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family.
  
 0.840
Q6FKS4_CANGA
Citrate synthase; Belongs to the citrate synthase family.
  
 
 0.793
Your Current Organism:
Candida glabrata
NCBI taxonomy Id: 284593
Other names: Candida glabrata ATCC 2001, Candida glabrata ATCC2001, Candida glabrata CBS 138, Candida glabrata CBS138, [. glabrata CBS 138, [Candida] glabrata CBS 138
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.