node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
HSP10 | HSP78 | Q6FRI5 | Q6FJ65 | Uncharacterized protein; Belongs to the GroES chaperonin family. | Uncharacterized protein; Belongs to the ClpA/ClpB family. | 0.738 |
HSP10 | PIM1 | Q6FRI5 | Q6FPE6 | Uncharacterized protein; Belongs to the GroES chaperonin family. | Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. | 0.776 |
HSP10 | Q6FQV2_CANGA | Q6FRI5 | Q6FQV2 | Uncharacterized protein; Belongs to the GroES chaperonin family. | Uncharacterized protein; Belongs to the heat shock protein 70 family. | 0.743 |
HSP10 | Q6FR25_CANGA | Q6FRI5 | Q6FR25 | Uncharacterized protein; Belongs to the GroES chaperonin family. | Uncharacterized protein; Belongs to the heat shock protein 70 family. | 0.745 |
HSP10 | Q6FT70_CANGA | Q6FRI5 | Q6FT70 | Uncharacterized protein; Belongs to the GroES chaperonin family. | Uncharacterized protein; Belongs to the heat shock protein 70 family. | 0.724 |
HSP10 | mge1 | Q6FRI5 | Q6FPH2 | Uncharacterized protein; Belongs to the GroES chaperonin family. | GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity). | 0.977 |
HSP78 | HSP10 | Q6FJ65 | Q6FRI5 | Uncharacterized protein; Belongs to the ClpA/ClpB family. | Uncharacterized protein; Belongs to the GroES chaperonin family. | 0.738 |
HSP78 | PIM1 | Q6FJ65 | Q6FPE6 | Uncharacterized protein; Belongs to the ClpA/ClpB family. | Lon protease homolog, mitochondrial; ATP-dependent serine protease that mediates the selective degradation of misfolded, unassembled or oxidatively damaged polypeptides as well as certain short-lived regulatory proteins in the mitochondrial matrix. May also have a chaperone function in the assembly of inner membrane protein complexes. Participates in the regulation of mitochondrial gene expression and in the maintenance of the integrity of the mitochondrial genome. Binds to mitochondrial DNA in a site-specific manner; Belongs to the peptidase S16 family. | 0.750 |
HSP78 | Q6FQV2_CANGA | Q6FJ65 | Q6FQV2 | Uncharacterized protein; Belongs to the ClpA/ClpB family. | Uncharacterized protein; Belongs to the heat shock protein 70 family. | 0.703 |
HSP78 | Q6FR25_CANGA | Q6FJ65 | Q6FR25 | Uncharacterized protein; Belongs to the ClpA/ClpB family. | Uncharacterized protein; Belongs to the heat shock protein 70 family. | 0.738 |
HSP78 | Q6FT70_CANGA | Q6FJ65 | Q6FT70 | Uncharacterized protein; Belongs to the ClpA/ClpB family. | Uncharacterized protein; Belongs to the heat shock protein 70 family. | 0.700 |
HSP78 | mge1 | Q6FJ65 | Q6FPH2 | Uncharacterized protein; Belongs to the ClpA/ClpB family. | GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity). | 0.864 |
PAM16 | PAM18 | Q6FT88 | Q6FPU1 | Mitochondrial import inner membrane translocase subunit TIM16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity); Belongs to the TIM16/PAM16 family. | Mitochondrial import inner membrane translocase subunit TIM14; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1) (By similarity); Belongs to the TIM14 family. | 0.993 |
PAM16 | Q6FPN3_CANGA | Q6FT88 | Q6FPN3 | Mitochondrial import inner membrane translocase subunit TIM16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity); Belongs to the TIM16/PAM16 family. | Mitochondrial import inner membrane translocase subunit TIM44; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner; Belongs to the Tim44 family. | 0.975 |
PAM16 | Q6FQV2_CANGA | Q6FT88 | Q6FQV2 | Mitochondrial import inner membrane translocase subunit TIM16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity); Belongs to the TIM16/PAM16 family. | Uncharacterized protein; Belongs to the heat shock protein 70 family. | 0.522 |
PAM16 | Q6FR25_CANGA | Q6FT88 | Q6FR25 | Mitochondrial import inner membrane translocase subunit TIM16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity); Belongs to the TIM16/PAM16 family. | Uncharacterized protein; Belongs to the heat shock protein 70 family. | 0.527 |
PAM16 | Q6FT70_CANGA | Q6FT88 | Q6FT70 | Mitochondrial import inner membrane translocase subunit TIM16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity); Belongs to the TIM16/PAM16 family. | Uncharacterized protein; Belongs to the heat shock protein 70 family. | 0.459 |
PAM16 | mge1 | Q6FT88 | Q6FPH2 | Mitochondrial import inner membrane translocase subunit TIM16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity); Belongs to the TIM16/PAM16 family. | GrpE protein homolog, mitochondrial; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of SSC1 to substrate proteins (By similarity). | 0.903 |
PAM18 | PAM16 | Q6FPU1 | Q6FT88 | Mitochondrial import inner membrane translocase subunit TIM14; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1) (By similarity); Belongs to the TIM14 family. | Mitochondrial import inner membrane translocase subunit TIM16; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to regulate activity of mtHSP70 (SSC1) via its interaction with PAM18/TIM14. May act by positioning PAM18/TIM14 in juxtaposition to mtHSP70 at the translocon to maximize ATPase stimulation (By similarity); Belongs to the TIM16/PAM16 family. | 0.993 |
PAM18 | Q6FL51_CANGA | Q6FPU1 | Q6FL51 | Mitochondrial import inner membrane translocase subunit TIM14; Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, it is required to stimulate activity of mtHSP70 (SSC1) (By similarity); Belongs to the TIM14 family. | Uncharacterized protein. | 0.963 |