node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AAH1 | ADO1 | Q6FP78 | Q6FWK4 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. | PfkB domain-containing protein. | 0.977 |
AAH1 | APT1 | Q6FP78 | Q6FSX4 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. | Pribosyltran domain-containing protein. | 0.762 |
AAH1 | GUA1 | Q6FP78 | Q6FUF3 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. | GMP synthase [glutamine-hydrolyzing]. | 0.717 |
AAH1 | ISN1 | Q6FP78 | Q6FLD4 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. | IMP-specific 5'-nucleotidase 1; IMP-specific 5'-nucleotidase involved in IMP (inositol monophosphate) degradation; Belongs to the ISN1 family. | 0.909 |
AAH1 | PURA_CANGA | Q6FP78 | Q6FMU9 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. | 0.665 |
AAH1 | Q6FM59_CANGA | Q6FP78 | Q6FM59 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.761 |
AAH1 | Q6FNM6_CANGA | Q6FP78 | Q6FNM6 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. | Pribosyltran domain-containing protein. | 0.704 |
AAH1 | Q6FNV3_CANGA | Q6FP78 | Q6FNV3 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.974 |
AAH1 | Q6FSW0_CANGA | Q6FP78 | Q6FSW0 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. | A_deaminase domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.647 |
AAH1 | Q6FWH8_CANGA | Q6FP78 | Q6FWH8 | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. | Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. | 0.646 |
ADO1 | AAH1 | Q6FWK4 | Q6FP78 | PfkB domain-containing protein. | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. | 0.977 |
ADO1 | APT1 | Q6FWK4 | Q6FSX4 | PfkB domain-containing protein. | Pribosyltran domain-containing protein. | 0.964 |
ADO1 | GUA1 | Q6FWK4 | Q6FUF3 | PfkB domain-containing protein. | GMP synthase [glutamine-hydrolyzing]. | 0.422 |
ADO1 | PURA_CANGA | Q6FWK4 | Q6FMU9 | PfkB domain-containing protein. | Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP (By similarity). Belongs to the adenylosuccinate synthetase family. | 0.728 |
ADO1 | Q6FM59_CANGA | Q6FWK4 | Q6FM59 | PfkB domain-containing protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. | 0.485 |
ADO1 | Q6FNM6_CANGA | Q6FWK4 | Q6FNM6 | PfkB domain-containing protein. | Pribosyltran domain-containing protein. | 0.960 |
ADO1 | Q6FNV3_CANGA | Q6FWK4 | Q6FNV3 | PfkB domain-containing protein. | Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate. | 0.970 |
ADO1 | Q6FSW0_CANGA | Q6FWK4 | Q6FSW0 | PfkB domain-containing protein. | A_deaminase domain-containing protein; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. | 0.962 |
APT1 | AAH1 | Q6FSX4 | Q6FP78 | Pribosyltran domain-containing protein. | Adenine deaminase; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily. | 0.762 |
APT1 | ADO1 | Q6FSX4 | Q6FWK4 | Pribosyltran domain-containing protein. | PfkB domain-containing protein. | 0.964 |