STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CMC4Cx9C motif-containing protein 4, mitochondrial; Belongs to the CMC4 family. (85 aa)    
Predicted Functional Partners:
CTRG_00675
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
   
 0.941
CTRG_02624
Histone H2B; Belongs to the histone H2B family.
   
 0.930
CTRG_00449
Histone H2A; Belongs to the histone H2A family.
   
 0.853
CTRG_03742
Ubiquitin.
   
 0.785
CTRG_05622
Ubiquitin.
   
 0.759
CTRG_03812
Cell division control protein 68.
   
 
 0.756
CTRG_03853
DNA-directed RNA polymerase II 45 kDa polypeptide.
    
 0.737
CTRG_04456
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
  0.737
CTRG_02012
Uncharacterized protein; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. SET2 subfamily.
    
 0.730
CTRG_01047
Uncharacterized protein; Belongs to the nucleosome assembly protein (NAP) family.
    
 
 0.726
Your Current Organism:
Candida tropicalis
NCBI taxonomy Id: 294747
Other names: C. tropicalis MYA-3404, Candida tropicalis MYA-3404, Candida tropicalis T1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.