STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
rlmDRNA methyltransferase, TrmA family; Catalyzes the formation of 5-methyl-uridine at position 1939 (m5U1939) in 23S rRNA; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family. RlmD subfamily. (447 aa)    
Predicted Functional Partners:
Fbal_0842
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
     0.762
Fbal_0843
MazG family protein; COGs: COG3956 Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain; InterPro IPR004518: IPR011551; KEGG: efe:EFER_0283 nucleoside triphosphate pyrophosphohydrolase; PFAM: MazG nucleotide pyrophosphohydrolase; SPTR: P0AEY3 Protein mazG; TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase domain; TIGRFAM: MazG family protein.
 
     0.745
Fbal_0840
COGs: COG0642 Signal transduction histidine kinase; InterPro IPR004358: IPR008207: IPR019247: IPR001789: IPR 003594: IPR003660: IPR003661: IPR005467; KEGG: sbp:Sbal223_1223 Hpt sensor hybrid histidine kinase; PFAM: Protein of unknown function DUF2222; Hpt domain protein; response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; SMART: response regulator receiver; histidine kinase A domain protein; Hpt domain protein; histidine kinase HAMP region domain protein; ATP-binding region ATPase domain [...]
  
    0.626
pyrG
CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.
  
    0.604
rsmF
16S rRNA m(5)C-1407 methyltransferase; Specifically methylates the cytosine at position 1407 (m5C1407) of 16S rRNA.
 
  
 0.590
trmB
tRNA (guanine-N(7)-)-methyltransferase; Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA.
 
  
 0.552
truD
tRNA pseudouridine synthase D TruD; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family.
  
  
 0.549
Fbal_0838
KEGG: sdn:Sden_0112 hypothetical protein; SPTR: A2PNM1 Putative uncharacterized protein; PFAM: Protein of unknown function (DUF2986).
       0.546
Fbal_0839
Protein of unknown function DUF416; COGs: COG3068 conserved hypothetical protein; InterPro IPR007338; KEGG: spl:Spea_1179 hypothetical protein; PFAM: protein of unknown function DUF416; SPTR: A2UZ88 Putative uncharacterized protein; PFAM: Protein of unknown function, DUF.
       0.546
Fbal_0021
16S rRNA m(5)C-967 methyltransferase; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA.
  
  
 0.531
Your Current Organism:
Ferrimonas balearica
NCBI taxonomy Id: 550540
Other names: F. balearica DSM 9799, Ferrimonas balearica DSM 9799, Ferrimonas balearica PAT, Ferrimonas balearica str. DSM 9799, Ferrimonas balearica strain DSM 9799
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