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hisZ protein (Dehalogenimonas lykanthroporepellens) - STRING interaction network
"hisZ" - histidine--tRNA ligase in Dehalogenimonas lykanthroporepellens
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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hisZhistidine--tRNA ligase; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (412 aa)    
Predicted Functional Partners:
Dehly_0653
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (466 aa)
 
 
  0.976
hisB
Imidazoleglycerol-phosphate dehydratase (196 aa)
   
   
  0.930
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (422 aa)
         
  0.924
hisC
Histidinol-phosphate aminotransferase (363 aa)
         
  0.904
pheT
phenylalanyl-tRNA synthetase subunit beta (812 aa)
   
   
  0.857
hisS
histidyl-tRNA synthetase (418 aa)
   
   
 
0.852
valS
valyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a "posttransfer" editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner (880 aa)
 
   
  0.830
Dehly_0881
Class II tRNA synthetase (300 aa)
   
 
  0.784
lysS
lysyl-tRNA synthetase (493 aa)
   
 
  0.784
alaS
alanyl-tRNA synthetase; Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction- alanine is first activated by ATP to form Ala- AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain (856 aa)
 
   
  0.771
Your Current Organism:
Dehalogenimonas lykanthroporepellens
NCBI taxonomy Id: 552811
Other names: Chloroflexi bacterium BL-DC-8, Chloroflexi bacterium BL-DC-9, D. lykanthroporepellens, D. lykanthroporepellens BL-DC-9, Dehalogenimonas, Dehalogenimonas lykanthroporepellens, Dehalogenimonas lykanthroporepellens BL-DC-9, Dehalogenimonas lykanthroporepellens str. BL-DC-9, Dehalogenimonas lykanthroporepellens strain BL-DC-9
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