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hisB protein (Dehalogenimonas lykanthroporepellens) - STRING interaction network
"hisB" - KEGG: deb:DehaBAV1_0761 imidazoleglycerol-phosphate dehydratase in Dehalogenimonas lykanthroporepellens
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
hisBKEGG- deb-DehaBAV1_0761 imidazoleglycerol-phosphate dehydratase; PFAM- imidazoleglycerol-phosphate dehydratase (196 aa)    
Predicted Functional Partners:
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (422 aa)
  0.999
hisC
KEGG- deb-DehaBAV1_0762 aminotransferase; TIGRFAM- histidinol-phosphate aminotransferase; PFAM- aminotransferase class I and II; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily (363 aa)
 
  0.999
hisF
Imidazole glycerol phosphate synthase subunit HisF; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (252 aa)
  0.999
hisH
Imidazole glycerol phosphate synthase subunit HisH; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (205 aa)
 
 
  0.997
hisI
Phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP (116 aa)
   
  0.993
Dehly_0713
PFAM- aminotransferase class I and II; KEGG- dev-DhcVS_593 histidinol-phosphate aminotransferase (362 aa)
 
  0.991
hisA
1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; TIGRFAM- phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; KEGG- deg-DehalGT_1067 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase; PFAM- histidine biosynthesis protein (281 aa)
   
  0.990
Dehly_0653
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (466 aa)
 
   
  0.976
hisZ
ATP phosphoribosyltransferase regulatory subunit; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (412 aa)
   
   
  0.873
Dehly_0476
PFAM- zinc/iron permease; KEGG- fpl-Ferp_1111 zinc/iron permease (244 aa)
 
            0.763
Your Current Organism:
Dehalogenimonas lykanthroporepellens
NCBI taxonomy Id: 552811
Other names: Chloroflexi bacterium BL-DC-8, Chloroflexi bacterium BL-DC-9, D. lykanthroporepellens BL-DC-9, Dehalogenimonas lykanthroporepellens, Dehalogenimonas lykanthroporepellens BL-DC-9, Dehalogenimonas lykanthroporepellens str. BL-DC-9, Dehalogenimonas lykanthroporepellens strain BL-DC-9
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