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hisB protein (Dehalogenimonas lykanthroporepellens) - STRING interaction network
"hisB" - Imidazoleglycerol-phosphate dehydratase in Dehalogenimonas lykanthroporepellens
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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Score
hisBImidazoleglycerol-phosphate dehydratase (196 aa)    
Predicted Functional Partners:
hisD
Histidinol dehydrogenase; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine (422 aa)
 
  0.999
hisC
Histidinol-phosphate aminotransferase (363 aa)
 
  0.999
hisH
Imidazole glycerol phosphate synthase glutamine amidotransferase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit provides the glutamine amidotransferase activity that produces the ammonia necessary to HisF for the synthesis of IGP and AICAR (205 aa)
 
 
  0.996
hisF
Imidazoleglycerol phosphate synthase cyclase subunit; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit (252 aa)
 
 
  0.996
Dehly_0713
Class I and II aminotransferase (362 aa)
 
  0.990
hisA
Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase (281 aa)
 
   
  0.967
Dehly_0653
ATP phosphoribosyltransferase; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N’-(5’-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity (466 aa)
 
   
  0.960
hisI
phosphoribosyl-AMP cyclohydrolase; Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP (116 aa)
 
   
  0.944
hisZ
histidine--tRNA ligase; Required for the first step of histidine biosynthesis. May allow the feedback regulation of ATP phosphoribosyltransferase activity by histidine (412 aa)
   
   
  0.930
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP (566 aa)
   
   
  0.786
Your Current Organism:
Dehalogenimonas lykanthroporepellens
NCBI taxonomy Id: 552811
Other names: Chloroflexi bacterium BL-DC-8, Chloroflexi bacterium BL-DC-9, D. lykanthroporepellens, D. lykanthroporepellens BL-DC-9, Dehalogenimonas, Dehalogenimonas lykanthroporepellens, Dehalogenimonas lykanthroporepellens BL-DC-9, Dehalogenimonas lykanthroporepellens str. BL-DC-9, Dehalogenimonas lykanthroporepellens strain BL-DC-9
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