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purD protein (Dehalogenimonas lykanthroporepellens) - STRING interaction network
"purD" - Phosphoribosylamine--glycine ligase in Dehalogenimonas lykanthroporepellens
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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purDPhosphoribosylamine--glycine ligase; PFAM- Phosphoribosylglycinamide synthetase, ATP-grasp (A) domain; Phosphoribosylglycinamide synthetase, N-domain; Phosphoribosylglycinamide synthetase, C-domain; manually curated; KEGG- deg-DehalGT_0718 phosphoribosylamine/glycine ligase; TIGRFAM- phosphoribosylamine/glycine ligase; Belongs to the GARS family (419 aa)    
Predicted Functional Partners:
purF
Amidophosphoribosyltransferase; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine (494 aa)
 
  0.998
purC
TIGRFAM- phosphoribosylaminoimidazole-succinocarboxamide synthase; KEGG- dev-DhcVS_745 phosphoribosylaminoimidazole-succinocarboxamide synthase; PFAM- SAICAR synthetase (304 aa)
 
  0.997
purH
Bifunctional purine biosynthesis protein PurH; SMART- AICARFT/IMPCHase bienzyme formylation region; TIGRFAM- phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; KEGG- dev-DhcVS_1199 phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase; PFAM- AICARFT/IMPCHase bienzyme formylation region; MGS domain protein (511 aa)
 
 
  0.997
purE
N5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR) (152 aa)
   
  0.995
purL
Phosphoribosylformylglycinamidine synthase subunit PurL; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (948 aa)
 
  0.993
Dehly_1201
Phosphoribosylformylglycinamidine synthase subunit PurQ; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP-dependent manner. PurS interacts with PurQ and PurL and is thought t [...] (257 aa)
 
  0.988
guaA
GMP synthase [glutamine-hydrolyzing]; Catalyzes the synthesis of GMP from XMP (566 aa)
 
   
  0.985
Dehly_0658
KEGG- deb-DehaBAV1_0759 adenylosuccinate lyase; TIGRFAM- adenylosuccinate lyase; PFAM- fumarate lyase; Adenylosuccinate lyase-like; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily (451 aa)
   
 
  0.974
Dehly_0686
PFAM- formyl transferase domain protein; KEGG- deb-DehaBAV1_0647 folate-dependent phosphoribosylglycinamide formyltransferase PurN-like protein (277 aa)
   
   
  0.973
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (415 aa)
   
   
  0.886
Your Current Organism:
Dehalogenimonas lykanthroporepellens
NCBI taxonomy Id: 552811
Other names: Chloroflexi bacterium BL-DC-8, Chloroflexi bacterium BL-DC-9, D. lykanthroporepellens BL-DC-9, Dehalogenimonas lykanthroporepellens, Dehalogenimonas lykanthroporepellens BL-DC-9, Dehalogenimonas lykanthroporepellens str. BL-DC-9, Dehalogenimonas lykanthroporepellens strain BL-DC-9
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