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folD protein (Dehalogenimonas lykanthroporepellens) - STRING interaction network
"folD" - Methenyltetrahydrofolate cyclohydrolase in Dehalogenimonas lykanthroporepellens
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second shell of interactors
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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folDMethenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10- methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10- formyltetrahydrofolate (295 aa)    
Predicted Functional Partners:
fhs
Formate--tetrahydrofolate ligase (588 aa)
 
  0.998
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF- independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism (415 aa)
   
  0.983
fmt
methionyl-tRNA formyltransferase; Modifies the free amino group of the aminoacyl moiety of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by- (I) promoting its recognition by IF2 and (II) impairing its binding to EFTu-GTP (318 aa)
 
 
  0.981
purH
Phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase (511 aa)
   
 
  0.972
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4) (284 aa)
   
 
  0.963
Dehly_0458
5,10-methylenetetrahydrofolate reductase (295 aa)
   
 
  0.951
Dehly_0848
FAD-dependent pyridine nucleotide-disulfide oxidoreductase (455 aa)
       
  0.924
Dehly_0677
Thymidylate synthase (215 aa)
   
 
  0.921
thyX
Thymidylate synthase; Catalyzes the formation of dTMP and tetrahydrofolate from dUMP and methylenetetrahydrofolate (196 aa)
       
  0.915
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP (566 aa)
   
   
  0.858
Your Current Organism:
Dehalogenimonas lykanthroporepellens
NCBI taxonomy Id: 552811
Other names: Chloroflexi bacterium BL-DC-8, Chloroflexi bacterium BL-DC-9, D. lykanthroporepellens, D. lykanthroporepellens BL-DC-9, Dehalogenimonas, Dehalogenimonas lykanthroporepellens, Dehalogenimonas lykanthroporepellens BL-DC-9, Dehalogenimonas lykanthroporepellens str. BL-DC-9, Dehalogenimonas lykanthroporepellens strain BL-DC-9
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