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groL protein (Dehalogenimonas lykanthroporepellens) - STRING interaction network
"groL" - Chaperonin GroEL in Dehalogenimonas lykanthroporepellens
Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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[Homology]
Score
groLChaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions (534 aa)    
Predicted Functional Partners:
groS
Chaperonin cpn10; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter (97 aa)
 
  0.999
dnaK
Chaperone protein DnaK; Acts as a chaperone (642 aa)
 
  0.998
grpE
GrpE protein HSP-70 cofactor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of [...] (173 aa)
   
  0.982
Dehly_1124
Diacylglycerol kinase catalytic-domain containing protein (295 aa)
       
    0.962
Dehly_0143
Diacylglycerol kinase catalytic-domain containing protein (309 aa)
       
    0.962
pheT
phenylalanyl-tRNA synthetase subunit beta (812 aa)
   
 
  0.956
Dehly_1412
Hydrogenase expression/formation protein HypD (363 aa)
     
      0.943
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate (306 aa)
     
 
  0.935
thrS
threonyl-tRNA synthetase (584 aa)
   
 
  0.930
Dehly_0708
Thioredoxin (105 aa)
   
 
  0.915
Your Current Organism:
Dehalogenimonas lykanthroporepellens
NCBI taxonomy Id: 552811
Other names: Chloroflexi bacterium BL-DC-8, Chloroflexi bacterium BL-DC-9, D. lykanthroporepellens, D. lykanthroporepellens BL-DC-9, Dehalogenimonas, Dehalogenimonas lykanthroporepellens, Dehalogenimonas lykanthroporepellens BL-DC-9, Dehalogenimonas lykanthroporepellens str. BL-DC-9, Dehalogenimonas lykanthroporepellens strain BL-DC-9
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