STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
MCYG_048453-phosphoshikimate 1-carboxyvinyltransferase; The AROM polypeptide catalyzes 5 consecutive enzymatic reactions in prechorismate polyaromatic amino acid biosynthesis. In the N-terminal section; belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. In the 3rd section; belongs to the shikimate kinase family. In the C-terminal section; belongs to the shikimate dehydrogenase family. (1571 aa)    
Predicted Functional Partners:
MCYG_01145
Chorismate synthase.
  
 
 0.959
MCYG_01660
Multifunctional tryptophan biosynthesis protein; Trifunctional enzyme bearing the Gln amidotransferase (GATase) domain of anthranilate synthase, indole-glycerolphosphate synthase, and phosphoribosylanthranilate isomerase activities.
  
 0.920
MCYG_00227
Phospho-2-dehydro-3-deoxyheptonate aldolase.
   
 
 0.899
MCYG_05501
Phospho-2-dehydro-3-deoxyheptonate aldolase.
   
 
 0.899
MCYG_02650
Phospho-2-dehydro-3-deoxyheptonate aldolase; Belongs to the class-II DAHP synthase family.
   
 0.893
MCYG_02923
Chorismate mutase.
  
 
 0.875
MCYG_03266
Anthranilate synthase component 1.
  
 
 0.810
MCYG_01951
Chorismate mutase/prephenate dehydratase.
    
 0.807
MCYG_00425
Histidine biosynthesis trifunctional protein.
  
  
 0.792
MCYG_00202
Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family.
  
 
 0.766
Your Current Organism:
Microsporum canis
NCBI taxonomy Id: 554155
Other names: Arthroderma otae CBS 113480, M. canis CBS 113480, Microsporum canis CBS 113480, Microsporum canis CBS113480
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.