STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EEG76138.1Putative RNA polymerase, sigma 28 subunit, FliA/WhiG subfamily; PFAM: sigma-70 region 4 domain protein; KEGG: pth:PTH_1122 DNA-directed RNA polymerase, sigma subunit. (71 aa)    
Predicted Functional Partners:
EEG78308.1
Sporulation transcriptional activator Spo0A; May play the central regulatory role in sporulation. It may be an element of the effector pathway responsible for the activation of sporulation genes in response to nutritional stress. Spo0A may act in concert with spo0H (a sigma factor) to control the expression of some genes that are critical to the sporulation process.
  
   
 0.777
EEG77108.1
Stage IV sporulation protein A; ATPase. Has a role at an early stage in the morphogenesis of the spore coat.
  
     0.770
EEG78783.1
TIGRFAM: stage V sporulation protein AE; PFAM: SpoVA protein; KEGG: ckl:CKL_1590 predicted stage V sporulation protein AE.
  
     0.764
EEG78311.1
TIGRFAM: stage IV sporulation protein B; PFAM: PDZ/DHR/GLGF domain protein; peptidase S55 SpoIVB; KEGG: sth:STH1833 stage IV sporulation protein B.
  
   
 0.760
EEG78782.1
TIGRFAM: stage V sporulation protein AD; PFAM: Stage V sporulation AD family protein; KEGG: amt:Amet_4224 stage V sporulation protein AD.
  
     0.750
EEG76630.1
TIGRFAM: sporulation protein YabP; PFAM: YabP family protein; KEGG: cth:Cthe_2659 YabP-like protein.
  
     0.750
EEG78781.1
TIGRFAM: stage V sporulation protein AC; PFAM: SpoVA protein; KEGG: amt:Amet_4225 sporulation stage V, protein AC.
  
     0.749
EEG77613.1
RNA polymerase, sigma 28 subunit, SigG; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.
 
   
 0.742
spoIIAB
Anti-sigma regulatory factor, serine/threonine protein kinase; Binds to sigma F and blocks its ability to form an RNA polymerase holoenzyme (E-sigma F). Phosphorylates SpoIIAA on a serine residue. This phosphorylation may enable SpoIIAA to act as an anti- anti-sigma factor that counteracts SpoIIAB and thus releases sigma F from inhibition.
  
   
 0.740
EEG78058.1
TIGRFAM: stage II sporulation protein P; PFAM: Stage II sporulation P family protein; KEGG: tte:TTE0947 stage II sporulation protein P.
  
     0.735
Your Current Organism:
Dethiobacter alkaliphilus
NCBI taxonomy Id: 555088
Other names: D. alkaliphilus AHT 1, Dethiobacter alkaliphilus AHT 1, Dethiobacter alkaliphilus DSM 19026, Dethiobacter alkaliphilus str. AHT 1, Dethiobacter alkaliphilus strain AHT 1
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