STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gshBKEGG: ppw:PputW619_0471 glutathione synthetase; TIGRFAM: glutathione synthetase; PFAM: glutathione synthetase ATP-binding; RimK domain protein ATP-grasp; glutathione synthetase domain protein; Belongs to the prokaryotic GSH synthase family. (321 aa)    
Predicted Functional Partners:
ACX95368.1
TIGRFAM: glutamate/cysteine ligase; PFAM: glutamate--cysteine ligase GshA; KEGG: tbd:Tbd_2408 glutamate--cysteine ligase GshA.
 
  
 0.986
ACX96991.1
PFAM: Redoxin domain protein; glutaredoxin; alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; KEGG: ava:Ava_4981 glutaredoxin-like region.
    
 0.939
pepA
Leucyl aminopeptidase; Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
   
 
 0.935
ACX96990.1
PFAM: pyridine nucleotide-disulphide oxidoreductase dimerisation region; FAD-dependent pyridine nucleotide-disulphide oxidoreductase; FAD dependent oxidoreductase; HI0933 family protein; KEGG: tcx:Tcr_0140 glutathione reductase.
     
 0.929
ACX96243.1
PFAM: glutathione peroxidase; KEGG: cti:RALTA_A0026 putative glutathione peroxydase; Belongs to the glutathione peroxidase family.
    
 0.921
ACX94892.1
KEGG: mrd:Mrad2831_1522 gamma-glutamyltransferase; TIGRFAM: gamma-glutamyltransferase; PFAM: gamma-glutamyltranspeptidase.
    
 0.908
ACX95870.1
TIGRFAM: aminopeptidase N; PFAM: Peptidase M1 membrane alanine aminopeptidase; KEGG: noc:Noc_1314 aminopeptidase N.
    
 0.905
ACX95356.1
Redoxin domain protein; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. Prx5 subfamily.
     
 0.901
glyA
Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
     
 0.800
ACX95366.1
ApbE family lipoprotein; Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein. Belongs to the ApbE family.
       0.716
Your Current Organism:
Halothiobacillus neapolitanus
NCBI taxonomy Id: 555778
Other names: H. neapolitanus c2, Halothiobacillus neapolitanus ATCC 23641, Halothiobacillus neapolitanus c2, Halothiobacillus neapolitanus str. c2, Halothiobacillus neapolitanus strain c2
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.