STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrFPyrF; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP); Belongs to the OMP decarboxylase family. Type 1 subfamily. (242 aa)    
Predicted Functional Partners:
pyrE
PyrE; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.995
carB
Carbamoyl-phosphate synthase large chain; Belongs to the CarB family.
 
  
 0.960
ubiB
UbiB; NAD(P)H-flavin reductase.
  
  
 0.956
pyrB
PyrB; Aspartate carbamoyltransferase catalytic subunit; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.954
upp
Upp; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.948
pyrH
PyrH; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.940
carA
CarA; Carbomyl phosphate synthetase small subunit; Belongs to the CarA family.
  
  
 0.939
surE
SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.918
lapB
Hypothetical protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
      0.863
LHK_00854
Dihydroorotate oxidase; Catalyzes the conversion of dihydroorotate to orotate.
 
  
 0.848
Your Current Organism:
Laribacter hongkongensis
NCBI taxonomy Id: 557598
Other names: L. hongkongensis HLHK9, Laribacter hongkongensis HLHK9, Laribacter hongkongensis str. HLHK9, Laribacter hongkongensis strain HLHK9
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