node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
LHK_01397 | panB | LHK_01397 | LHK_01398 | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.888 |
LHK_01397 | panC | LHK_01397 | LHK_01399 | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.691 |
LHK_01397 | panD | LHK_01397 | LHK_01400 | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | PanD; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.468 |
LHK_01397 | risB | LHK_01397 | LHK_02389 | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | RisB; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.520 |
LHK_02555 | panB | LHK_02555 | LHK_01398 | Hypothetical protein. | PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.713 |
LHK_02555 | panC | LHK_02555 | LHK_01399 | Hypothetical protein. | PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.962 |
LHK_02555 | panD | LHK_02555 | LHK_01400 | Hypothetical protein. | PanD; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.404 |
coaX | dfp | LHK_03253 | LHK_01909 | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | Dfp; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.944 |
coaX | panC | LHK_03253 | LHK_01399 | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.968 |
coaX | panD | LHK_03253 | LHK_01400 | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | PanD; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.702 |
dfp | coaX | LHK_01909 | LHK_03253 | Dfp; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantothenate kinase; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis; Belongs to the type III pantothenate kinase family. | 0.944 |
dfp | panB | LHK_01909 | LHK_01398 | Dfp; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 0.581 |
dfp | panC | LHK_01909 | LHK_01399 | Dfp; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.916 |
flaG | panC | LHK_02704 | LHK_01399 | FlaG; Uncharacterized flagellar protein FlaG. | PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.619 |
goaG | panC | LHK_02823 | LHK_01399 | GoaG; 4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.903 |
goaG | panD | LHK_02823 | LHK_01400 | GoaG; 4-aminobutyrate transaminase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | PanD; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.913 |
kcy | panC | LHK_00868 | LHK_01399 | Kcy; Cytidylate kinase. | PanC; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.913 |
panB | LHK_01397 | LHK_01398 | LHK_01397 | PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | 7, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase. | 0.888 |
panB | LHK_02555 | LHK_01398 | LHK_02555 | PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Hypothetical protein. | 0.713 |
panB | dfp | LHK_01398 | LHK_01909 | PanB; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. | Dfp; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.581 |