STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ppcPhosphoenolpyruvate carboxylase; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle; Belongs to the PEPCase type 1 family. (879 aa)    
Predicted Functional Partners:
pckA
Phosphoenolpyruvate carboxykinase; Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA. Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.
     
 0.967
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate.
     
 0.964
pykA
Pyruvate kinase; COG:G;COG0469; Belongs to the pyruvate kinase family.
     
 0.930
eno
Phosphopyruvate hydratase/enolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.
   
 
 0.927
gltA
Type II citrate synthase; COG:C;COG0372; Belongs to the citrate synthase family.
     
 0.851
fdxH
Formate dehydrogenase iron-sulfur subunit; The beta chain is an electron transfer unit containing 4 cysteine clusters involved in the formation of iron-sulfur centers.
     
 0.809
fdxG_2
Formate dehydrogenase major subunit; COG:C;COG0243.
     
 0.804
fdxG_1
Formate dehydrogenase major subunit; COG:C;COG0243; Belongs to the prokaryotic molybdopterin-containing oxidoreductase family.
     
 0.804
fdxI
Formate dehydrogenase cytochrome B556 subunit, gamma subunit; COG:C;COG2864.
     
  0.800
purU
Formyltetrahydrofolate deformylase; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4).
     
  0.800
Your Current Organism:
Glaesserella parasuis
NCBI taxonomy Id: 557723
Other names: G. parasuis SH0165, Glaesserella parasuis SH0165, Haemophilus parasuis SH0165
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