STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sodCSuperoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (180 aa)    
Predicted Functional Partners:
sodA
Manganese superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family.
   
 
 0.900
hprA
Glycerate dehydrogenase; COG:CHR;COG1052; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
   
   0.702
cysK
Cysteine synthase; COG:E;COG0031; Belongs to the cysteine synthase/cystathionine beta- synthase family.
   
  
 0.639
tonB
TobB energy transducing protein; Interacts with outer membrane receptor proteins that carry out high-affinity binding and energy dependent uptake into the periplasmic space of specific substrates. It could act to transduce energy from the cytoplasmic membrane to specific energy-requiring processes in the outer membrane, resulting in the release into the periplasm of ligands bound by these outer membrane proteins. Belongs to the TonB family.
      
 0.634
rec2
Competence protein ComEC; COG:R;COG0658.
      
 0.632
lspA
Lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family.
      
 0.616
tonB-2
Periplasmic protein, links inner and outer membranes.
      
 0.605
nanH
Neuraminidase/exo-alpha-sialidase nanH; COG:G;COG4409.
   
  
 0.604
rseA
sigma-E factor negative regulatory protein; An anti-sigma factor for extracytoplasmic function (ECF) sigma factor sigma-E (RpoE). ECF sigma factors are held in an inactive form by an anti-sigma factor until released by regulated intramembrane proteolysis (RIP). RIP occurs when an extracytoplasmic signal triggers a concerted proteolytic cascade to transmit information and elicit cellular responses. The membrane-spanning regulatory substrate protein is first cut periplasmically (site-1 protease, S1P, DegS), then within the membrane itself (site-2 protease, S2P, RseP), while cytoplasmic p [...]
      
 0.601
rpoE
RNA polymerase sigma-70 factor; COG:K;COG1595; Belongs to the sigma-70 factor family. ECF subfamily.
      
 0.588
Your Current Organism:
Glaesserella parasuis
NCBI taxonomy Id: 557723
Other names: G. parasuis SH0165, Glaesserella parasuis SH0165, Haemophilus parasuis SH0165
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