STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AA0117_g808HMG box domain-containing protein. (106 aa)    
Predicted Functional Partners:
AA0117_g3983
Histone H2A; Belongs to the histone H2A family.
   
 0.836
A0A177D4Y2
SPT16-domain-containing protein.
   
 0.741
A0A177E3T0
FACT complex subunit POB3; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of [...]
   
 0.728
A0A177DF09
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
    
 0.704
AA0117_g1412
Actin-related protein 8; Probably involved in transcription regulation via its interaction with the INO80 complex, a chromatin remodeling complex. Belongs to the actin family.
    
 0.648
A0A177DN63
RNA polymerase II transcription factor.
    
 0.593
A0A177DRY2
Transcription factor Tfb4.
    
 0.579
AA0117_g9488
TFIIH basal transcription factor complex helicase XPB subunit.
   
 0.566
AA0117_g9629
RuvB-like helicase; DNA helicase participates in several chromatin remodeling complexes, including the SWR1 and the INO80 complexes.
    
 0.563
A0A177DX67
Actin-like ATPase domain-containing protein; Belongs to the actin family.
    
 0.559
Your Current Organism:
Alternaria alternata
NCBI taxonomy Id: 5599
Other names: A. alternata, ATCC 66981 [[Alternaria tenuis]], Alternaria sp. AltIEIHBT, Alternaria sp. Ao34, Alternaria sp. Ao41, Alternaria sp. JZ017, Alternaria sp. M2-2, Alternaria sp. XJU-1, Alternaria tenuis, CBS 916.96 [[Alternaria tenuis]], EGS 34-016 [[Alternaria tenuis]], IMI 254138 [[Alternaria tenuis]], Torula alternata
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.