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glmU protein (Mycobacterium abscessus) - STRING interaction network
"glmU" - Bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase in Mycobacterium abscessus
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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glmUBifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP- GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5- monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain (482 aa)    
Predicted Functional Partners:
glmM
Phosphoglucosamine mutase MrsA; Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate (438 aa)
 
  0.988
murA
UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine (412 aa)
 
  0.954
glmS
Glucosamine--fructose-6-phosphate aminotransferase; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source (621 aa)
 
  0.924
prs
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of ribose 1,5-bisphosphate. Catalyzes the transfer of pyrophosphoryl group from ATP to ribose- 5-phosphate to yield phosphoribosyl diphosphate (PRPP) and AMP (328 aa)
 
   
  0.914
MAB_4226c
Phosphate acetyltransferase; Involved in acetate metabolism (693 aa)
   
 
  0.829
MAB_3603c
Phosphomannomutase/phosphoglucomutase (469 aa)
   
  0.734
MAB_3661
Phosphomannomutase PmmB (537 aa)
   
  0.733
MAB_1149
TetR family transcriptional regulator (214 aa)
              0.728
murC
UDP-N-acetylmuramate--L-alanine ligase; Cell wall formation (490 aa)
 
 
  0.702
MAB_1086
Putative UTP-glucose-1-phosphate uridylyltransferase (309 aa)
 
 
  0.649
Your Current Organism:
Mycobacterium abscessus
NCBI taxonomy Id: 561007
Other names: M. abscessus, M. abscessus ATCC 19977, M. abscessus subgroup, M. chelonae group, Mycobacterium abscessus, Mycobacterium abscessus ATCC 19977, Mycobacterium abscessus str. ATCC 19977, Mycobacterium abscessus strain ATCC 19977, Mycobacterium abscessus subgroup, Mycobacterium abscessus subsp. abscessus, Mycobacterium chelonae group, Mycobacterium chelonae subsp. abscessus, Mycobacterium chelonei subsp. abscessus
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