node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PC1_0249 | msrP | PC1_0249 | PC1_0247 | TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: eca:ECA0265 putative zinc-binding oxidoreductase. | Oxidoreductase molybdopterin binding; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce b [...] | 0.483 |
PC1_1015 | msrP | PC1_1015 | PC1_0247 | PFAM: alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen; Redoxin domain protein; KEGG: eca:ECA1117 peroxidase. | Oxidoreductase molybdopterin binding; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce b [...] | 0.419 |
PC1_1489 | PC1_1515 | PC1_1489 | PC1_1515 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: eca:ECA2814 molybdopterin synthase small subunit. | 0.852 |
PC1_1489 | PC1_1516 | PC1_1489 | PC1_1516 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | PFAM: molybdopterin biosynthesis MoaE protein; KEGG: eca:ECA2813 molybdopterin synthase large subunit. | 0.942 |
PC1_1489 | moaA | PC1_1489 | PC1_1512 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.917 |
PC1_1489 | moaC | PC1_1489 | PC1_1514 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.938 |
PC1_1489 | msrP | PC1_1489 | PC1_0247 | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | Oxidoreductase molybdopterin binding; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce b [...] | 0.587 |
PC1_1515 | PC1_1489 | PC1_1515 | PC1_1489 | TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: eca:ECA2814 molybdopterin synthase small subunit. | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.852 |
PC1_1515 | PC1_1516 | PC1_1515 | PC1_1516 | TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: eca:ECA2814 molybdopterin synthase small subunit. | PFAM: molybdopterin biosynthesis MoaE protein; KEGG: eca:ECA2813 molybdopterin synthase large subunit. | 0.999 |
PC1_1515 | moaA | PC1_1515 | PC1_1512 | TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: eca:ECA2814 molybdopterin synthase small subunit. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.927 |
PC1_1515 | moaC | PC1_1515 | PC1_1514 | TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: eca:ECA2814 molybdopterin synthase small subunit. | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.983 |
PC1_1515 | msrP | PC1_1515 | PC1_0247 | TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: eca:ECA2814 molybdopterin synthase small subunit. | Oxidoreductase molybdopterin binding; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce b [...] | 0.419 |
PC1_1516 | PC1_1489 | PC1_1516 | PC1_1489 | PFAM: molybdopterin biosynthesis MoaE protein; KEGG: eca:ECA2813 molybdopterin synthase large subunit. | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.942 |
PC1_1516 | PC1_1515 | PC1_1516 | PC1_1515 | PFAM: molybdopterin biosynthesis MoaE protein; KEGG: eca:ECA2813 molybdopterin synthase large subunit. | TIGRFAM: molybdopterin converting factor, subunit 1; PFAM: thiamineS protein; KEGG: eca:ECA2814 molybdopterin synthase small subunit. | 0.999 |
PC1_1516 | moaA | PC1_1516 | PC1_1512 | PFAM: molybdopterin biosynthesis MoaE protein; KEGG: eca:ECA2813 molybdopterin synthase large subunit. | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | 0.979 |
PC1_1516 | moaC | PC1_1516 | PC1_1514 | PFAM: molybdopterin biosynthesis MoaE protein; KEGG: eca:ECA2813 molybdopterin synthase large subunit. | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.999 |
PC1_1516 | msrP | PC1_1516 | PC1_0247 | PFAM: molybdopterin biosynthesis MoaE protein; KEGG: eca:ECA2813 molybdopterin synthase large subunit. | Oxidoreductase molybdopterin binding; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce b [...] | 0.637 |
PC1_1516 | msrQ | PC1_1516 | PC1_0246 | PFAM: molybdopterin biosynthesis MoaE protein; KEGG: eca:ECA2813 molybdopterin synthase large subunit. | Ferric reductase domain protein protein transmembrane component domain protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for re [...] | 0.444 |
PC1_3730 | msrP | PC1_3730 | PC1_0247 | Peroxiredoxin; Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides; Belongs to the peroxiredoxin family. AhpC/Prx1 subfamily. | Oxidoreductase molybdopterin binding; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce b [...] | 0.419 |
moaA | PC1_1489 | PC1_1512 | PC1_1489 | Molybdenum cofactor biosynthesis protein A; Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate. | Molybdenum cofactor synthesis domain protein; Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP. Belongs to the MoeA family. | 0.917 |