node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PC1_1224 | PC1_1226 | PC1_1224 | PC1_1226 | Deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: eca:ECA1349 deoxyribodipyrimidine photolyase. | PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: eca:ECA1351 putative allophanate hydrolase subunit 1. | 0.552 |
PC1_1224 | PC1_1227 | PC1_1224 | PC1_1227 | Deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: eca:ECA1349 deoxyribodipyrimidine photolyase. | Urea amidolyase related protein; KEGG: eca:ECA1352 putative allophanate hydrolase subunit 2; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2. | 0.546 |
PC1_1224 | nei | PC1_1224 | PC1_1230 | Deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: eca:ECA1349 deoxyribodipyrimidine photolyase. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.568 |
PC1_1224 | pcp | PC1_1224 | PC1_1229 | Deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: eca:ECA1349 deoxyribodipyrimidine photolyase. | Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family. | 0.481 |
PC1_1224 | pxpA | PC1_1224 | PC1_1228 | Deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: eca:ECA1349 deoxyribodipyrimidine photolyase. | LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. | 0.596 |
PC1_1226 | PC1_1224 | PC1_1226 | PC1_1224 | PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: eca:ECA1351 putative allophanate hydrolase subunit 1. | Deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: eca:ECA1349 deoxyribodipyrimidine photolyase. | 0.552 |
PC1_1226 | PC1_1227 | PC1_1226 | PC1_1227 | PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: eca:ECA1351 putative allophanate hydrolase subunit 1. | Urea amidolyase related protein; KEGG: eca:ECA1352 putative allophanate hydrolase subunit 2; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2. | 0.999 |
PC1_1226 | nei | PC1_1226 | PC1_1230 | PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: eca:ECA1351 putative allophanate hydrolase subunit 1. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.793 |
PC1_1226 | pcp | PC1_1226 | PC1_1229 | PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: eca:ECA1351 putative allophanate hydrolase subunit 1. | Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family. | 0.756 |
PC1_1226 | pxpA | PC1_1226 | PC1_1228 | PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: eca:ECA1351 putative allophanate hydrolase subunit 1. | LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. | 0.999 |
PC1_1227 | PC1_1224 | PC1_1227 | PC1_1224 | Urea amidolyase related protein; KEGG: eca:ECA1352 putative allophanate hydrolase subunit 2; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2. | Deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: eca:ECA1349 deoxyribodipyrimidine photolyase. | 0.546 |
PC1_1227 | PC1_1226 | PC1_1227 | PC1_1226 | Urea amidolyase related protein; KEGG: eca:ECA1352 putative allophanate hydrolase subunit 2; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2. | PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: eca:ECA1351 putative allophanate hydrolase subunit 1. | 0.999 |
PC1_1227 | nei | PC1_1227 | PC1_1230 | Urea amidolyase related protein; KEGG: eca:ECA1352 putative allophanate hydrolase subunit 2; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.781 |
PC1_1227 | pcp | PC1_1227 | PC1_1229 | Urea amidolyase related protein; KEGG: eca:ECA1352 putative allophanate hydrolase subunit 2; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2. | Pyrrolidone-carboxylate peptidase; Removes 5-oxoproline from various penultimate amino acid residues except L-proline; Belongs to the peptidase C15 family. | 0.761 |
PC1_1227 | pxpA | PC1_1227 | PC1_1228 | Urea amidolyase related protein; KEGG: eca:ECA1352 putative allophanate hydrolase subunit 2; TIGRFAM: urea amidolyase related protein; PFAM: Allophanate hydrolase subunit 2; SMART: Allophanate hydrolase subunit 2. | LamB/YcsF family protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate. | 0.999 |
coaE | nei | PC1_3579 | PC1_1230 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.690 |
coaE | nth | PC1_3579 | PC1_2019 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Endonuclease III; DNA repair enzyme that has both DNA N-glycosylase activity and AP-lyase activity. The DNA N-glycosylase activity releases various damaged pyrimidines from DNA by cleaving the N-glycosidic bond, leaving an AP (apurinic/apyrimidinic) site. The AP-lyase activity cleaves the phosphodiester bond 3' to the AP site by a beta-elimination, leaving a 3'-terminal unsaturated sugar and a product with a terminal 5'- phosphate. | 0.463 |
coaE | polA | PC1_3579 | PC1_4227 | dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.623 |
nei | PC1_1224 | PC1_1230 | PC1_1224 | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Deoxyribodipyrimidine photo-lyase; PFAM: DNA photolyase FAD-binding; DNA photolyase domain protein; KEGG: eca:ECA1349 deoxyribodipyrimidine photolyase. | 0.568 |
nei | PC1_1226 | PC1_1230 | PC1_1226 | DNA-(apurinic or apyrimidinic site) lyase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized pyrimidines, such as thymine glycol, 5,6-dihydrouracil and 5,6-dihydrothymine. Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | PFAM: Allophanate hydrolase subunit 1; SMART: Allophanate hydrolase subunit 1; KEGG: eca:ECA1351 putative allophanate hydrolase subunit 1. | 0.793 |