node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PC1_0360 | PC1_1102 | PC1_0360 | PC1_1102 | KEGG: eca:ECA0375 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | PFAM: ribonucleotide reductase; KEGG: eca:ECA1198 ribonucleotide-diphosphate reductase subunit beta. | 0.457 |
PC1_0360 | PC1_3388 | PC1_0360 | PC1_3388 | KEGG: eca:ECA0375 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: eca:ECA3568 nucleoside triphosphate pyrophosphohydrolase. | 0.900 |
PC1_0360 | dcd | PC1_0360 | PC1_1290 | KEGG: eca:ECA0375 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.907 |
PC1_0360 | dut | PC1_0360 | PC1_4102 | KEGG: eca:ECA0375 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.927 |
PC1_0360 | ndk | PC1_0360 | PC1_3018 | KEGG: eca:ECA0375 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.916 |
PC1_0360 | pyrG | PC1_0360 | PC1_3387 | KEGG: eca:ECA0375 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | CTP synthase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.911 |
PC1_1102 | PC1_0360 | PC1_1102 | PC1_0360 | PFAM: ribonucleotide reductase; KEGG: eca:ECA1198 ribonucleotide-diphosphate reductase subunit beta. | KEGG: eca:ECA0375 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | 0.457 |
PC1_1102 | PC1_1103 | PC1_1102 | PC1_1103 | PFAM: ribonucleotide reductase; KEGG: eca:ECA1198 ribonucleotide-diphosphate reductase subunit beta. | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.998 |
PC1_1102 | PC1_4034 | PC1_1102 | PC1_4034 | PFAM: ribonucleotide reductase; KEGG: eca:ECA1198 ribonucleotide-diphosphate reductase subunit beta. | PFAM: protein of unknown function DUF413; KEGG: eca:ECA4231 hypothetical protein. | 0.439 |
PC1_1102 | dcd | PC1_1102 | PC1_1290 | PFAM: ribonucleotide reductase; KEGG: eca:ECA1198 ribonucleotide-diphosphate reductase subunit beta. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.530 |
PC1_1102 | ndk | PC1_1102 | PC1_3018 | PFAM: ribonucleotide reductase; KEGG: eca:ECA1198 ribonucleotide-diphosphate reductase subunit beta. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.912 |
PC1_1103 | PC1_1102 | PC1_1103 | PC1_1102 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | PFAM: ribonucleotide reductase; KEGG: eca:ECA1198 ribonucleotide-diphosphate reductase subunit beta. | 0.998 |
PC1_1103 | dcd | PC1_1103 | PC1_1290 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.599 |
PC1_1103 | dut | PC1_1103 | PC1_4102 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Deoxyuridine 5'-triphosphate nucleotidohydrolase Dut; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. | 0.710 |
PC1_1103 | ndk | PC1_1103 | PC1_3018 | Ribonucleoside-diphosphate reductase, alpha subunit; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.916 |
PC1_1291 | dcd | PC1_1291 | PC1_1290 | PFAM: AsmA family protein; KEGG: eca:ECA1413 putative assembly protein. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.621 |
PC1_1291 | udk | PC1_1291 | PC1_1289 | PFAM: AsmA family protein; KEGG: eca:ECA1413 putative assembly protein. | KEGG: eca:ECA1411 uridine kinase; TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase. | 0.416 |
PC1_3388 | PC1_0360 | PC1_3388 | PC1_0360 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: eca:ECA3568 nucleoside triphosphate pyrophosphohydrolase. | KEGG: eca:ECA0375 anaerobic ribonucleoside triphosphate reductase; TIGRFAM: anaerobic ribonucleoside-triphosphate reductase; PFAM: formate C-acetyltransferase glycine radical; ATP-cone domain protein. | 0.900 |
PC1_3388 | dcd | PC1_3388 | PC1_1290 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: eca:ECA3568 nucleoside triphosphate pyrophosphohydrolase. | Deoxycytidine triphosphate deaminase; Catalyzes the deamination of dCTP to dUTP. | 0.917 |
PC1_3388 | ndk | PC1_3388 | PC1_3018 | TIGRFAM: MazG family protein; PFAM: MazG nucleotide pyrophosphohydrolase; KEGG: eca:ECA3568 nucleoside triphosphate pyrophosphohydrolase. | Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.900 |