STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cddCytidine deaminase; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis. (296 aa)    
Predicted Functional Partners:
PC1_4067
Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the PNP/UDP phosphorylase family.
 
 
 0.980
deoA
Thymidine phosphorylase; The enzymes which catalyze the reversible phosphorolysis of pyrimidine nucleosides are involved in the degradation of these compounds and in their utilization as carbon and energy sources, or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.
 
 
 0.960
deoD
TIGRFAM: purine nucleoside phosphorylase; PFAM: purine or other phosphorylase family 1; KEGG: eca:ECA0730 purine nucleoside phosphorylase.
  
 
 0.931
udk
KEGG: eca:ECA1411 uridine kinase; TIGRFAM: uridine kinase; PFAM: phosphoribulokinase/uridine kinase.
    
 0.929
tdk
PFAM: thymidine kinase; KEGG: eca:ECA2327 thymidine kinase.
    
 0.927
PC1_1083
PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: eca:ECA1184 bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor; Belongs to the 5'-nucleotidase family.
    
 0.913
PC1_3422
TIGRFAM: 2',3'-cyclic-nucleotide 2'-phosphodiesterase; PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: eca:ECA3602 bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein; Belongs to the 5'-nucleotidase family.
    
 0.906
PC1_4198
PFAM: 5'-Nucleotidase domain protein; metallophosphoesterase; KEGG: eca:ECA0053 putative phosphodiesterase; Belongs to the 5'-nucleotidase family.
    
 0.906
PC1_2775
Metal dependent phosphohydrolase; Catalyzes the strictly specific dephosphorylation of 2'- deoxyribonucleoside 5'-monophosphates.
     
 0.901
ppnP
Protein of unknown function DUF1255; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.900
Your Current Organism:
Pectobacterium carotovorum
NCBI taxonomy Id: 561230
Other names: P. carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum PC1, Pectobacterium carotovorum subsp. carotovorum str. PC1, Pectobacterium carotovorum subsp. carotovorum strain PC1
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