node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PC1_3146 | PC1_3147 | PC1_3146 | PC1_3147 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: eca:ECA3350 bifunctional chorismate mutase/prephenate dehydratase. | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: eca:ECA3351 bifunctional chorismate mutase/prephenate dehydrogenase. | 0.987 |
PC1_3146 | PC1_3668 | PC1_3146 | PC1_3668 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: eca:ECA3350 bifunctional chorismate mutase/prephenate dehydratase. | Aspartate kinase; KEGG: eca:ECA3891 bifunctional aspartokinase I/homeserine dehydrogenase I; TIGRFAM: aspartate kinase; PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; aspartate/glutamate/uridylate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.725 |
PC1_3146 | aroA | PC1_3146 | PC1_1733 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: eca:ECA3350 bifunctional chorismate mutase/prephenate dehydratase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.878 |
PC1_3146 | aroB | PC1_3146 | PC1_3882 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: eca:ECA3350 bifunctional chorismate mutase/prephenate dehydratase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.644 |
PC1_3146 | aroC | PC1_3146 | PC1_2811 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: eca:ECA3350 bifunctional chorismate mutase/prephenate dehydratase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.980 |
PC1_3146 | aroE | PC1_3146 | PC1_3784 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: eca:ECA3350 bifunctional chorismate mutase/prephenate dehydratase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.634 |
PC1_3146 | aroK | PC1_3146 | PC1_3883 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: eca:ECA3350 bifunctional chorismate mutase/prephenate dehydratase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.679 |
PC1_3146 | aroL | PC1_3146 | PC1_0997 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: eca:ECA3350 bifunctional chorismate mutase/prephenate dehydratase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. | 0.674 |
PC1_3146 | cmk | PC1_3146 | PC1_1734 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: eca:ECA3350 bifunctional chorismate mutase/prephenate dehydratase. | TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: eca:ECA2592 cytidylate kinase. | 0.569 |
PC1_3146 | serC | PC1_3146 | PC1_1732 | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: eca:ECA3350 bifunctional chorismate mutase/prephenate dehydratase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.851 |
PC1_3147 | PC1_3146 | PC1_3147 | PC1_3146 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: eca:ECA3351 bifunctional chorismate mutase/prephenate dehydrogenase. | TIGRFAM: chorismate mutase; PFAM: prephenate dehydratase; Chorismate mutase; KEGG: eca:ECA3350 bifunctional chorismate mutase/prephenate dehydratase. | 0.987 |
PC1_3147 | PC1_3668 | PC1_3147 | PC1_3668 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: eca:ECA3351 bifunctional chorismate mutase/prephenate dehydrogenase. | Aspartate kinase; KEGG: eca:ECA3891 bifunctional aspartokinase I/homeserine dehydrogenase I; TIGRFAM: aspartate kinase; PFAM: homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding; aspartate/glutamate/uridylate kinase; In the C-terminal section; belongs to the homoserine dehydrogenase family. | 0.791 |
PC1_3147 | aroA | PC1_3147 | PC1_1733 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: eca:ECA3351 bifunctional chorismate mutase/prephenate dehydrogenase. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.973 |
PC1_3147 | aroB | PC1_3147 | PC1_3882 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: eca:ECA3351 bifunctional chorismate mutase/prephenate dehydrogenase. | 3-dehydroquinate synthase; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ); Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family. | 0.863 |
PC1_3147 | aroC | PC1_3147 | PC1_2811 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: eca:ECA3351 bifunctional chorismate mutase/prephenate dehydrogenase. | Chorismate synthase; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.996 |
PC1_3147 | aroE | PC1_3147 | PC1_3784 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: eca:ECA3351 bifunctional chorismate mutase/prephenate dehydrogenase. | Shikimate 5-dehydrogenase; Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). | 0.627 |
PC1_3147 | aroK | PC1_3147 | PC1_3883 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: eca:ECA3351 bifunctional chorismate mutase/prephenate dehydrogenase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. | 0.684 |
PC1_3147 | aroL | PC1_3147 | PC1_0997 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: eca:ECA3351 bifunctional chorismate mutase/prephenate dehydrogenase. | Shikimate kinase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate. | 0.684 |
PC1_3147 | cmk | PC1_3147 | PC1_1734 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: eca:ECA3351 bifunctional chorismate mutase/prephenate dehydrogenase. | TIGRFAM: cytidylate kinase; PFAM: cytidylate kinase region; KEGG: eca:ECA2592 cytidylate kinase. | 0.478 |
PC1_3147 | serC | PC1_3147 | PC1_1732 | TIGRFAM: chorismate mutase; PFAM: Chorismate mutase; Prephenate dehydrogenase; KEGG: eca:ECA3351 bifunctional chorismate mutase/prephenate dehydrogenase. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.795 |