node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PC1_0299 | PC1_0578 | PC1_0299 | PC1_0578 | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: eca:ECA0312 glutamate synthase subunit alpha. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.491 |
PC1_0299 | PC1_2456 | PC1_0299 | PC1_2456 | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: eca:ECA0312 glutamate synthase subunit alpha. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.482 |
PC1_0299 | asd | PC1_0299 | PC1_3940 | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: eca:ECA0312 glutamate synthase subunit alpha. | Aspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.646 |
PC1_0299 | purR | PC1_0299 | PC1_2388 | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: eca:ECA0312 glutamate synthase subunit alpha. | Transcriptional regulator, LacI family; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.623 |
PC1_0572 | PC1_0578 | PC1_0572 | PC1_0578 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.999 |
PC1_0572 | PC1_2389 | PC1_0572 | PC1_2389 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: eca:ECA1924 cyclopropane fatty acyl phospholipid synthase. | 0.473 |
PC1_0572 | purR | PC1_0572 | PC1_2388 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | Transcriptional regulator, LacI family; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.589 |
PC1_0578 | PC1_0299 | PC1_0578 | PC1_0299 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: eca:ECA0312 glutamate synthase subunit alpha. | 0.491 |
PC1_0578 | PC1_0572 | PC1_0578 | PC1_0572 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | 0.999 |
PC1_0578 | PC1_2389 | PC1_0578 | PC1_2389 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: eca:ECA1924 cyclopropane fatty acyl phospholipid synthase. | 0.510 |
PC1_0578 | PC1_2456 | PC1_0578 | PC1_2456 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | 0.478 |
PC1_0578 | purR | PC1_0578 | PC1_2388 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | Transcriptional regulator, LacI family; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.605 |
PC1_1013 | purR | PC1_1013 | PC1_2388 | PFAM: amino acid permease-associated region; KEGG: eca:ECA1115 putative proline-specific permease. | Transcriptional regulator, LacI family; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.656 |
PC1_2389 | PC1_0572 | PC1_2389 | PC1_0572 | PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: eca:ECA1924 cyclopropane fatty acyl phospholipid synthase. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | 0.473 |
PC1_2389 | PC1_0578 | PC1_2389 | PC1_0578 | PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: eca:ECA1924 cyclopropane fatty acyl phospholipid synthase. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.510 |
PC1_2389 | purR | PC1_2389 | PC1_2388 | PFAM: Cyclopropane-fatty-acyl-phospholipid synthase; Methyltransferase type 11; Methyltransferase type 12; KEGG: eca:ECA1924 cyclopropane fatty acyl phospholipid synthase. | Transcriptional regulator, LacI family; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.443 |
PC1_2456 | PC1_0299 | PC1_2456 | PC1_0299 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | PFAM: ferredoxin-dependent glutamate synthase; glutamate synthase alpha subunit domain protein; glutamate synthase; glutamine amidotransferase class-II; KEGG: eca:ECA0312 glutamate synthase subunit alpha. | 0.482 |
PC1_2456 | PC1_0578 | PC1_2456 | PC1_0578 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.478 |
PC1_2456 | folE | PC1_2456 | PC1_1670 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | KEGG: eca:ECA2711 GTP cyclohydrolase I; TIGRFAM: GTP cyclohydrolase I; PFAM: GTP cyclohydrolase I. | 0.489 |
PC1_2456 | purR | PC1_2456 | PC1_2388 | Phosphoenolpyruvate synthase; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family. | Transcriptional regulator, LacI family; Is the main repressor of the genes involved in the de novo synthesis of purine nucleotides, regulating purB, purC, purEK, purF, purHD, purL, purMN and guaBA expression. PurR is allosterically activated to bind its cognate DNA by binding the purine corepressors, hypoxanthine or guanine, thereby effecting transcription repression. | 0.447 |