node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PC1_0211 | PC1_0213 | PC1_0211 | PC1_0213 | TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: eca:ECA0228 thiamine biosynthesis protein ThiH. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: eca:ECA0229A sulfur carrier protein ThiS. | 0.963 |
PC1_0211 | PC1_0214 | PC1_0211 | PC1_0214 | TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: eca:ECA0228 thiamine biosynthesis protein ThiH. | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: eca:ECA0230 thiamine biosynthesis protein ThiF. | 0.978 |
PC1_0211 | PC1_2979 | PC1_0211 | PC1_2979 | TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: eca:ECA0228 thiamine biosynthesis protein ThiH. | KEGG: eca:ECA3196 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.631 |
PC1_0211 | thiC | PC1_0211 | PC1_0216 | TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: eca:ECA0228 thiamine biosynthesis protein ThiH. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.984 |
PC1_0211 | thiE | PC1_0211 | PC1_0215 | TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: eca:ECA0228 thiamine biosynthesis protein ThiH. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.981 |
PC1_0211 | thiG | PC1_0211 | PC1_0212 | TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: eca:ECA0228 thiamine biosynthesis protein ThiH. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.999 |
PC1_0211 | thiM | PC1_0211 | PC1_2980 | TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: eca:ECA0228 thiamine biosynthesis protein ThiH. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.539 |
PC1_0213 | PC1_0211 | PC1_0213 | PC1_0211 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: eca:ECA0229A sulfur carrier protein ThiS. | TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: eca:ECA0228 thiamine biosynthesis protein ThiH. | 0.963 |
PC1_0213 | PC1_0214 | PC1_0213 | PC1_0214 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: eca:ECA0229A sulfur carrier protein ThiS. | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: eca:ECA0230 thiamine biosynthesis protein ThiF. | 0.998 |
PC1_0213 | PC1_2979 | PC1_0213 | PC1_2979 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: eca:ECA0229A sulfur carrier protein ThiS. | KEGG: eca:ECA3196 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.780 |
PC1_0213 | thiC | PC1_0213 | PC1_0216 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: eca:ECA0229A sulfur carrier protein ThiS. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.960 |
PC1_0213 | thiE | PC1_0213 | PC1_0215 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: eca:ECA0229A sulfur carrier protein ThiS. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.968 |
PC1_0213 | thiG | PC1_0213 | PC1_0212 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: eca:ECA0229A sulfur carrier protein ThiS. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.994 |
PC1_0213 | thiM | PC1_0213 | PC1_2980 | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: eca:ECA0229A sulfur carrier protein ThiS. | Hydroxyethylthiazole kinase; Catalyzes the phosphorylation of the hydroxyl group of 4- methyl-5-beta-hydroxyethylthiazole (THZ); Belongs to the Thz kinase family. | 0.495 |
PC1_0214 | PC1_0211 | PC1_0214 | PC1_0211 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: eca:ECA0230 thiamine biosynthesis protein ThiF. | TIGRFAM: thiazole biosynthesis protein ThiH; PFAM: biotin and thiamin synthesis associated; Radical SAM domain protein; KEGG: eca:ECA0228 thiamine biosynthesis protein ThiH. | 0.978 |
PC1_0214 | PC1_0213 | PC1_0214 | PC1_0213 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: eca:ECA0230 thiamine biosynthesis protein ThiF. | TIGRFAM: thiamine biosynthesis protein ThiS; PFAM: thiamineS protein; KEGG: eca:ECA0229A sulfur carrier protein ThiS. | 0.998 |
PC1_0214 | PC1_2979 | PC1_0214 | PC1_2979 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: eca:ECA0230 thiamine biosynthesis protein ThiF. | KEGG: eca:ECA3196 phosphomethylpyrimidine kinase; TIGRFAM: phosphomethylpyrimidine kinase; PFAM: Phosphomethylpyrimidine kinase type-1. | 0.638 |
PC1_0214 | thiC | PC1_0214 | PC1_0216 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: eca:ECA0230 thiamine biosynthesis protein ThiF. | Thiamine biosynthesis protein ThiC; Catalyzes the synthesis of the hydroxymethylpyrimidine phosphate (HMP-P) moiety of thiamine from aminoimidazole ribotide (AIR) in a radical S-adenosyl-L-methionine (SAM)-dependent reaction. | 0.964 |
PC1_0214 | thiE | PC1_0214 | PC1_0215 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: eca:ECA0230 thiamine biosynthesis protein ThiF. | Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family. | 0.974 |
PC1_0214 | thiG | PC1_0214 | PC1_0212 | PFAM: UBA/THIF-type NAD/FAD binding protein; MoeZ/MoeB domain protein; KEGG: eca:ECA0230 thiamine biosynthesis protein ThiF. | Thiazole biosynthesis family protein; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. | 0.977 |