node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PC1_0572 | PC1_0578 | PC1_0572 | PC1_0578 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.999 |
PC1_0572 | PC1_2347 | PC1_0572 | PC1_2347 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: eca:ECA1972 enoyl-(acyl carrier protein) reductase. | 0.772 |
PC1_0572 | PC1_3297 | PC1_0572 | PC1_3297 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | PFAM: Protein of unknown function DUF1974; acyl-CoA dehydrogenase domain protein; KEGG: eca:ECA3474 acyl-CoA dehydrogenase. | 0.531 |
PC1_0572 | acpP | PC1_0572 | PC1_2502 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.894 |
PC1_0572 | bioC | PC1_0572 | PC1_1507 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.434 |
PC1_0572 | bioF | PC1_0572 | PC1_1506 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.462 |
PC1_0572 | bioH | PC1_0572 | PC1_3924 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | bioH protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.578 |
PC1_0578 | PC1_0572 | PC1_0578 | PC1_0572 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | 0.999 |
PC1_0578 | PC1_2347 | PC1_0578 | PC1_2347 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: eca:ECA1972 enoyl-(acyl carrier protein) reductase. | 0.784 |
PC1_0578 | PC1_3297 | PC1_0578 | PC1_3297 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | PFAM: Protein of unknown function DUF1974; acyl-CoA dehydrogenase domain protein; KEGG: eca:ECA3474 acyl-CoA dehydrogenase. | 0.623 |
PC1_0578 | acpP | PC1_0578 | PC1_2502 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.976 |
PC1_0578 | bioC | PC1_0578 | PC1_1507 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.483 |
PC1_0578 | bioF | PC1_0578 | PC1_1506 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | 8-amino-7-oxononanoate synthase; Catalyzes the decarboxylative condensation of pimeloyl-[acyl- carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide. | 0.538 |
PC1_0578 | bioH | PC1_0578 | PC1_3924 | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | bioH protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.784 |
PC1_2347 | PC1_0572 | PC1_2347 | PC1_0572 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: eca:ECA1972 enoyl-(acyl carrier protein) reductase. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | 0.772 |
PC1_2347 | PC1_0578 | PC1_2347 | PC1_0578 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: eca:ECA1972 enoyl-(acyl carrier protein) reductase. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.784 |
PC1_2347 | acpP | PC1_2347 | PC1_2502 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: eca:ECA1972 enoyl-(acyl carrier protein) reductase. | Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis; Belongs to the acyl carrier protein (ACP) family. | 0.787 |
PC1_2347 | bioH | PC1_2347 | PC1_3924 | PFAM: short-chain dehydrogenase/reductase SDR; KEGG: eca:ECA1972 enoyl-(acyl carrier protein) reductase. | bioH protein; The physiological role of BioH is to remove the methyl group introduced by BioC when the pimeloyl moiety is complete. It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway through the hydrolysis of the ester bonds of pimeloyl-ACP esters. | 0.912 |
PC1_3297 | PC1_0572 | PC1_3297 | PC1_0572 | PFAM: Protein of unknown function DUF1974; acyl-CoA dehydrogenase domain protein; KEGG: eca:ECA3474 acyl-CoA dehydrogenase. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; Thioesterase; phosphopantetheine-binding; condensation domain protein; KEGG: mxa:MXAN_4000 non-ribosomal peptide synthetase. | 0.531 |
PC1_3297 | PC1_0578 | PC1_3297 | PC1_0578 | PFAM: Protein of unknown function DUF1974; acyl-CoA dehydrogenase domain protein; KEGG: eca:ECA3474 acyl-CoA dehydrogenase. | TIGRFAM: amino acid adenylation domain protein; PFAM: AMP-dependent synthetase and ligase; phosphopantetheine-binding; condensation domain protein; KEGG: rso:RS05859 peptide synthetase protein; Belongs to the ATP-dependent AMP-binding enzyme family. | 0.623 |